Pain, Postoperative
Conditions
Interventions
30 patients were randomly divided into 02 groups of 15 individuals. They received spinal anesthesia with 20 mg of 0.5% heavy bupivacaine associated with 75 mcg of morphine.
Lipoic Acid Group (GAL) rec
Drug
Procedure/surgery
E03.091
Sponsors
Instituto Doutor José Frota
Universidade Federal do Ceará
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients older than 18 years and less than 65 years of age, of both sexes, with physical status ASA I and ASA II according to the American Society of Anesthesiologists (ASA) Anesthetic Care Guidelines, scheduled for elective surgery in femur fracture correction
Exclusion criteria
Exclusion criteria: Volunteers who were hypersensitive to any of the drugs used in the study, who were pregnant, had kidney disease, coagulation disorder, puncture site infection, clinical signs of hypovolemia, who could not collaborate with the evaluation of postoperative analgesia and users of illicit drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of postoperative analgesia, measured by analog scale of pain and decreased postoperative opioid consumption;Não houve alteração no grau de dor pela escala analógica visual ou no consumo de opioide no pós-operatório | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 1: reduction of lipid peroxidation in the trans and post-operative, by measuring levels of Tbars, nitrite land Glutathione;Found outcome1: reduction of lipid peroxidation in transoperatorio, by the decrease in blood levels of Tbars. Without change in other markers;Expected outcome 2: to increase the satisfaction with the anesthetic technique;Outcome found 2: no difference in satisfaction with the anesthetic technique | — |
Countries
Brazil
Contacts
Public ContactAndressa Costa
Instituto Doutor José Frota
Outcome results
None listed