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Effect of Ozonated Water on Bad Breath and Clinical Parameters in Patients with Periodontitis

Effect of Ozonized Water on Halitosis and clinical parameters of patients with Periodontal Disease: A randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-95qzc2s
Enrollment
Unknown
Registered
2023-01-10
Start date
2022-04-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Halitosis

Interventions

This is a randomized, double-blind, parallel-group clinical trial that will last 4 weeks. In total, 62 patients with moderate to severe Periodontal Disease will be part of the sample, they will be ide
G2 – Conventional treatment (Scraping and root planing) and ozonated water. Both ozonated water and placebo will be used with an ultrasonic device. The treatments will be carried out twice a week and
Clinical outcomes of Periodontal Disease (gingival attachment index, probing depth index, tooth mobility index, dental calculus index, dental biofilm index, furcation involvement index, gingival bleed

Sponsors

Faculdade de Odontologia da Universidade de Passo Fundo
Lead Sponsor
Faculdade de Odontologia da Universidade de Passo Fundo
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Complaint of halitosis in the presence of periodontal disease; over 18 years of age; moderate to severe generalized periodontitis

Exclusion criteria

Exclusion criteria: Illiteracy; halitosis only by tongue coating; non-oral halitosis; acute oral lesions or necrotizing ulcerative periodontitis; use of antibiotics in the last 90 days; pregnancy or breastfeeding; decompensated systemic diseases

Design outcomes

Primary

MeasureTime frame
Assess halitosis using the organoleptic method (stratified from 0 to 5) and halimeter (measured in parts per billion). It is expected that after 30 days of treatment, numbers will drop and halitosis will decrease in both groups

Secondary

MeasureTime frame
Evaluate the clinical parameters of Periodontal Disease (probing depth index, gingival bleeding, tooth mobility and dental plaque) with a Williams millimeter probe and visual examination. It is expected that after 30 days of treatment, these parameters decrease in both groups;Microbiological analysis of periodontal pathogens will be performed by polymerase chain reaction (PCR) using a commercial test (Micro-IDentplus, Hain Lifescience, Nehren, Germany. It is expected that after 30 days of treatment, there will be a reduction in number of these pathogens

Countries

Brazil

Contacts

Public ContactLeonardo Saraiva

Universidade de Passo Fundo

leo77saraiva@hotmail.com+5554999999911

Outcome results

None listed

Source: REBEC (via WHO ICTRP)