Primary open angle glaucoma
Conditions
Interventions
This is a randomized controlled clinical trial with two arms in patients with glaucoma using at least three hypotensive eye drops from different classes. Experimental group: 26 glaucoma individuals wi
Sponsors
Universidade Federal de São Paulo
Universidade Federal de São Paulo
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 18 years old; both genders; diagnosed with glaucoma (determined by at least 2 criteria: intraocular pressure without eye drops above 21mmHg; typical defect in perimetry; localized damage in the nerve fiber layer); using at least 3 different classes of hypotensive eye drops; informed consent form granted
Exclusion criteria
Exclusion criteria: Patients with a history of ocular surface disease; intraocular surgeries (except cataract surgery); ocular trauma; secondary glaucomas; current use of contact lenses; systemic medications that may alter the tear film; steroids; or intolerance to any of the study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the efficacy of Triplenex (fixed triple combination) compared to the same substances separated into three eye drops (Bimatoprost 0.03%, Timolol Maleate 0.5%, and Brimonidine Tartrate 0.2%);Evaluate the adverse effects of Triplenex (fixed triple combination) compared to the same substances separated into three eye drops (Bimatoprost 0.03%, Timolol Maleate 0.5%, and Brimonidine Tartrate 0.2%) | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate the adherence of patients using the fixed combination compared to the use of the same three drugs separately;Evaluate the quality of life of patients using the fixed combination compared to the use of the same three drugs separately | — |
Countries
Brazil
Contacts
Public ContactLilian Machado
Universidade Federal de São Paulo
Outcome results
None listed