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Efficacy of In-office Bleaching immediately and 72 hours after its manipulation

Efficacy of In-office Bleaching with Attachable Syringe: immediate and after 72 hours of mixing: randomized, triple-blind equivalence clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-95jnbpt
Enrollment
Unknown
Registered
2025-07-31
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin Sensitivity

Interventions

The objective of this randomized controlled, triple-blind, split-mouth clinical trial is to evaluate the efficacy, tooth sensitivity, gingival irritation, and aesthetic self-perception associated with

Sponsors

Universidade Estadual de Ponta Grossa
Lead Sponsor
Universidade Estadual de Ponta Grossa
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Volunteers aged at least 18 years; both sexes; with good general and oral health; with teeth free of caries and periodontal disease in the anterior region; who agree to the free and informed consent form and whose canines must have A2 color or darker according to the Vita Classical scale (Vita Zahnfabrik, Bad Säckingen, Germany)

Exclusion criteria

Exclusion criteria: Volunteers who have previously undergone a whitening procedure; who have reported the presence of previous dental sensitivity; presence of dental prosthesis; fixed orthodontic appliance; restorations in the upper anterior teeth; endodontic treatment in the upper anterior teeth; gingival recessions; teeth with tetracycline staining or fluorosis; continuous use of medications such as analgesics and anti-inflammatories; pregnant or lactating women and those with habits such as bruxism

Design outcomes

Primary

MeasureTime frame
To evaluate the bleaching efficacy of participants undergoing in-office whitening with 35% hydrogen peroxide in a coupled syringe, applied either immediately or 72 hours after preparation, will be evaluated using the Vita Classical and Vita Bleachedguide shade scales, as well as the Vita Easyshade spectrophotometer.

Secondary

MeasureTime frame
Absolute risk of tooth sensitivity Data collected immediately after the bleaching session, up to 1h after, up to 24h after and up to 48h after the procedure, in each session, using the VAS scale (0-10). Percentage of patients with itooth sensitivity will be called absolute risk of tooth sensitivity;Absolute risk of gingival irritation. Data collected immediately after the bleaching session, up to 1h after, up to 24h after and up to 48h after the procedure, in each session, using the VAS scale (0-10). Percentage of patients with gingival irritation will be called absolute risk of gingival irritation.

Countries

Brazil

Contacts

Public ContactAlessandro Loguercio

Universidade Estadual de Ponta Grossa

aloguercio@hotmail.com+55 (42) 3220-3740

Outcome results

None listed

Source: REBEC (via WHO ICTRP)