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Assessment of eye inflammation after intravitreal injection injection

Randomized, double-blind clinical trial to evaluate inflammation following intravitreal injection - -: -

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-95ddhp
Enrollment
Unknown
Registered
2019-12-05
Start date
2019-07-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Iridocyclitis

Interventions

40 eyes of 40 subjects with usual indication for intravitreal anti-VEGF injection 48 to 72 hours before vitrectomy, in order to reduce the occurrence of intraoperative hemorrhage. The study will be di
Procedure/surgery

Sponsors

Universidade Federal de São Paulo
Lead Sponsor
Universidade Federal de São Paulo
Collaborator

Eligibility

Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Patients with indication for intravitreal anti-VEGF injection followed by vitrectomy to treat complications of diabetic retinopathy.

Exclusion criteria

Exclusion criteria: Glaucoma; previous or current history of uveitis; previous vitreoretinal surgery; patients who have contraindications to the use of anti-VEGF.

Design outcomes

Primary

MeasureTime frame
Increased eye inflammation in the agitated group in the laboratory, by measuring cytokine levels in aqueous humor using the Cytometric Bead Assay method;Increased eye inflammation in the agitated group in the laboratory, by measuring cytokine levels in aqueous humor using the Cytometric Bead Assay method

Secondary

MeasureTime frame
Não são esperados desfechos secundários

Countries

Brazil

Contacts

Public ContactMichel Farah

Universidade Federal de São Paulo

mefarah@uol.com.br+55115576-4981

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 17, 2026