Gallic Acid
Conditions
Interventions
This is a randomized, double-blind, controlled clinical trial with two parallel groups. Experimental group: 47 patients with squamous cell carcinoma of the head and neck undergoing radiotherapy treatm
biochemical tests including complete blood count, albumin, prealbumin, total cholesterol and fractions, triglycerides, glucose, glycated hemoglobin, and C-reactive protein
dietary intake analysis through a 24-hour recall classified according to the Food Guide for the Brazilian Population
and food acceptance assessment through structured interviews on preferences, aversions, and taste alterations analyzed using the IRAMUTEQ softwa
Sponsors
Universidade Estadual de Montes Claros
Universidade Estadual de Montes Claros
Eligibility
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 20 years of age. Both sexes. Diagnosis and treatment of head and neck cancer in a hospital participating in the study. Participation voluntarily authorized through signing of the Free and Informed Consent Form. Presence on the scheduled days for data collection and nutritional assessment
Exclusion criteria
Exclusion criteria: Patients who discontinue cancer treatment or do not follow the instructions related to the use of the dietary supplement. Patients with allergies or intolerance to any ingredient of the formula. Diabetic patients. Patients using feeding tubes. Oncology patients with neoplasms in anatomical sites other than the head and neck. Patients not identified by the researchers. Patients who refuse to participate or have not signed the Free and Informed Consent Form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the role of gallic acid in the modulation of molecular, biochemical, and morphological parameters in patients with head and neck cancer through the analysis of inflammatory, antioxidant, and nutritional biomarkers collected before and after the nutritional intervention with the dietary supplement containing gallic acid | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected that the use of the dietary supplement with the addition of gallic acid will be able to modulate squamous cells in patients with head and neck cancer influencing morphological molecular and nutritional parameters evaluated before and after the nutritional intervention and contributing to increased survival rates and improved patient well-being | — |
Countries
Brazil
Contacts
Public ContactAndré Guimarães
Universidade Estadual de Montes Claros
Outcome results
None listed