hip and knee prosthetic joint infection Sonication. Arthroplasty. Prosthesis-related infections /diagnosis. Biofilm. Tissue Culture Techniques.
Conditions
Interventions
Prosthesis replacement due to suspected infection
Tissue and sonication culture
146 patients
E04.690
C01.685
Sponsors
Faculdade de Ciências Médicas da Santa Casa de São Paulo
Faculdade de Ciências Médicas da Santa Casa de São Paulo
Eligibility
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: All patients who underwent total and partial hip and knee arthroplasties, with the implant removed for sonication.
Exclusion criteria
Exclusion criteria: Absence of collection of peri-prosthetic tissue in the intraoperative moment; Obvious contamination of orthopedic implants during their removal and/ or transport; Patients whose arthroplasties were not submitted to sonication due to the unavailability of suitable containers for transporting the implant at the time of removal or the absence of containers in the institution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the performance of implant sonication cultures compared to tissue cultures in the diagnosis of prosthetic joint infection, using the modified clinical criterion, and the diagnostic criteria proposed by International Consensus Meeting (ICM), Infectious Disease Society of America (IDSA) e European Bone and Joint Society (EBJIS); were used to compare the performance of microbiological tests McNemar´s test and proportion comparison were employed to calculate p-value; sensitivity, specificity, positive predictive value, negative predictive value and accuracy of each test were calculated using the proposed diagnostic criteria.;Describe the epidemiological aspects of the patients; descriptive; mean, median and standard deviation were calculated for numerical variables. | — |
Secondary
| Measure | Time frame |
|---|---|
| Describe the microbiological profile of infections of primary joint prosthesis and revision prosthesis; descriptive;Describe cultures with discordant and discrepant pathogens found in the two different tests used (tissue culture and sonicated fluid); descriptive | — |
Countries
Brazil
Contacts
Public ContactTaiana Ribeiro
Outcome results
None listed