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Oral cleaning in intensive care unit patients with photodynamic therapy

Oral hygiene in intensive care unit patients using photodynamic therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-94bvrc
Enrollment
Unknown
Registered
2016-06-08
Start date
2016-05-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator-associated pneumonia due to bad oral hygiene (bacterial infection)

Interventions

The oral hygiene procedure in all patientes is going to be done with gaze soaked in the solution determined by randomization. Oral hygiene will be done in upper and lower hemiarcade, teeth and palate
Drug
Device
Procedure/surgery
E02.774
D02.078.370.141.100

Sponsors

Universidade Nove de Julho
Lead Sponsor
Universidade Nove de Julho
Collaborator

Eligibility

Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Intensive care unit patient with 0 to 24h oro-tracheal intubation; patients whose family agree with the participation on this study and sign the agreement term; both genders, above 18 years old

Exclusion criteria

Exclusion criteria: Reintubation; readmission in Intensive Care Unit (ICU); smokers and ex-smokers for less than 5 years

Design outcomes

Primary

MeasureTime frame
Reduction in oral bacteria amount in one intervention analysed by real-time PCR (polimerase chain reaction), comparing pre and post intervention samples

Secondary

MeasureTime frame
Reduction in ventilator-associated pneumonia incidence in photodynamic therapy groups, doing daily the intervention and evaluating presence/absence of pneumonia after 5-8 days of treatment by analysis of medical cards

Countries

Brazil

Contacts

Public ContactGabriela da Collina

Universidade Nove de Julho

gabrielacollina@gmail.com+5511954476621

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Mar 9, 2026