Knee Osteoarthritis
Conditions
Interventions
75 individuals, 50 years old and over, with knee osteoarthritis will be aleatory allocated into two groups:
1) Experimental groups: individuals will be divided into 4 subgroups that will perform knee-
b) 80% of BFR without load (n=15)
c) 40% of BFR with low load (n=15)
and d) 80% of BFR with loe load (n=15)
2)Control group (n=15): individuals will perform knee-extension training with high load of 80% of maximum repetition (MR) associated with placebo BFR
The train
Other
G11.427.410.698.277
Sponsors
Universidade Federal do Amapá
Universidade Federal do Amapá
Eligibility
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Individuals of both sexes will be included; 50 years old and over; diagnosed with bilateral or unilateral knee osteoarthritis (OA) according to American College of Rheumatology criteria; moderate tosevere (scores between 5 and 13 on the Lequesne Questionnaire); with a minimum score of 24 points in the Mini Mental State Examination and who sign the Informed Consent Form (ICF)
Exclusion criteria
Exclusion criteria: Individuals with a history of surgery or any invasive procedure of the affected knee(s) will be excluded; who have undergone a physical therapy or strengthening program for knee injuries in the past three months; planned events, such as knee replacement or travel, which may interfere with individuals' participation during the study period; history of acute myocardial infarction and / or stroke; history of peripheral arterial disease and / or deep vein thrombosis; history of cancer that has generated limitations or restrictions to physical exercise; decompensated systemic blood pressure without medical supervision and changes in dose or type of anti-inflammatory or analgesic drugs in the last three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate knee joint pain levels before and after treatment, using the Visual Analogue Scale (VAS) of Pain considering the anchoring points that vary from 0 mm of the line "without pain" and "worst pain imaginable" in 100 mm of the line | — |
Secondary
| Measure | Time frame |
|---|---|
| To investigate the severity of osteoarthritis, using two instruments: the Lequesne Algofunctional Index and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), from scores of their total scores ranging from 0 (without involvement) to 24 (extremely severe) ) and 0 (best health) to 100 (worst possible health) respectively;Assess the functional level through the instruments: a) Time Get Up and Go Test (TUG), considered changed if the time to perform the test exceeds 12 seconds b) 30 second Chair Stand Test (30sCST), when classifying physical performance as reduced if repetitions less than or equal to 8 are performed in 30 seconds, and not reduced when the number of repetitions is greater than 8 c) 40m Fast Paced Walk Test (40mFPW), through clinically significant improvement if there is a minimum increase of 0.2 meters per second in the average speed of the route taken after the intervention d) Clinical Test of Sensory Interaction and Balance Modified, by staying for 30 seconds in six sensory conditions. If any instability occurs before 30 seconds the test is finished and considered changed;Evaluate the level of physical activity, using the Brazilian version of the International Physical Activity Questionaire (IPAQ), long version, by calculating the estimated energy expenditure in METs (metabolic equivalent);Evaluate the muscle strength of the knee extensors using the MicroFET2® manual dynamometer (Hogan Scientific - USA), from the knee extension in an isometric and maximum way for 3 to 5 seconds, in which three measurements of the evaluated limb will be performed, with rest 60 seconds between each assessment, considered the highest peak force value between the three measurements;Evaluate quality of life, using the Brazilian version of the generic SF-36 quality of life questionnaire, through the score of 8 domains ranging from 0 to 100, in which the highest score reflects the best function;to investigate discomfort during sessions, using | — |
Countries
Brazil
Contacts
Public ContactAreolino;Natália Matos;Iosimuta
Universidade Federal do Amapá;Universidade Federal do Amapá
Outcome results
None listed