Gingival recession
Conditions
Interventions
The study is a randomized controlled, split-mouth clinical trial. Patients will be randomly assigned to one of the two groups below:Group CHX: use of the toothpaste (Zinc Citrate 2%
Pyrophosphate and Sodium Fluoride 1,450 ppm) and rinse (chlorhexidine gluconate 0.12%). PHY group: use of the dental gel and topical gel of Phthalocyanine (0.1%)
Both groups will use the agents for th
root surfaces without abrasion, erosion or caries, systemically healthy patients, without contraindication for periodontal surgical procedures. Exclusion criteria will be: rotated, extruded, or comorb
Sponsors
Universidade de São Paulo
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients of both genders; aged between 18 and 70 years old; clinical diagnosis of multiple gingival recessions RT1 with at least 1 gingival recession = 2 mm, including canines and premolars; root surfaces without abrasion, erosion, or caries; systemically healthy patients; no contraindication for periodontal surgical procedures.
Exclusion criteria
Exclusion criteria: Rotated teeth; extruded or mobile teeth; smokers; pregnant and lactating individuals; history of periodontal disease or recurrent abscess formation; patients previously undergone root coverage surgical procedures; patients using medications [anticonvulsants, antihypertensives, contraceptives, or immunosuppressants]; low level of oral hygiene (plaque index and bleeding index >20%)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluating the remaining wound area (RWA) will be considered the primary outcome variable. The method for assessment will be performed using Image J software - NIH, Bethesda, USA. A minimum detectable difference of 30% in the remaining wound area (WRA) and a standard deviation of 5 mm² were assumed | — |
Secondary
| Measure | Time frame |
|---|---|
| The thickness of the palatal masticatory mucosa will be evaluated under anesthesia before the procedure and 2 months after the procedure through four fixed points (at 5 and 7 mm from the gingival margin) in the donor area. A guide will be made to standardize the points to be measured. ET will be measured using a periodontal probe with an endodontic stop at the 4 marked points until touching the palatal bone tissue. The distance between the stop and the tip of the probe will be measured in millimeters using a digital caliper | — |
Countries
Brazil
Contacts
Public ContactMariana Calefi
Universidade de São Paulo
Outcome results
None listed