Xerostomia
Conditions
Interventions
This is a controlled, crossover, two-arm clinical study aimed at evaluating the salivary response to different mechanical sialogogues to improve the diagnosis of salivary conditions. The sample consis
Sponsors
Faculdade de Ciências de Saúde da Universidade de Brasília
Hospital Universitário de Brasília
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: For Group 1, participants must be over 18 years old, of both sexes, in good systemic health, and without comorbidities such as hypertension, diabetes mellitus, or immunosuppressive diseases. They must be non-smokers, and alcohol consumption should be socially moderate. Additionally, alcohol consumption is not allowed within 24 hours prior to the collection. For Group 2, participants must be over 18 years old and exhibit symptoms of xerostomia
Exclusion criteria
Exclusion criteria: For Group 1, individuals who are using medications known to negatively affect salivary flow or induce xerostomia, including antihistamines, antidepressants, and anxiolytics, will be excluded. Smokers and heavy drinkers will also be excluded, as well as participants who consumed alcohol within 24 hours before the sialometry session. For Group 2, participants who do not present symptoms of xerostomia will be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Using the different sialagogues, an average difference in stimulated salivary flow is expected to be found, measured in milliliters per minute. Data will be collected from two sialometry sessions using the hyperboloid and paraffin wax sialagogues | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to identify an average difference in stimulated salivary flow when using the paraffin wax sialagogue, resulting in greater saliva production. The quantification will be carried out by measuring the volume of saliva produced per minute for each participant | — |
Countries
Brazil
Contacts
Public ContactValéria Carneiro
Faculdade de Ciências de Saúde da Universidade de Brasília
Outcome results
None listed