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Prevention of radiation induced dermatitis in cancer patients

Prevention of radiodermatitis in cancer patients: a randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
REBEC
Registry ID
RBR-92cts3
Enrollment
Unknown
Registered
2019-10-03
Start date
2019-05-13
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radiodermatitis

Interventions

1) Control group: usual care (n=50) 2) Experimental Group: usual care + topical application of Chamomilla recutita liposomal gel (n=50). The patients will apply the gel since the begging of radiothera
Drug
B01.650.940.800.575.912.250.100.509
D25.479.517

Sponsors

Universidade de Brasília
Lead Sponsor
Hospital Universitário de Brasília
Collaborator
University of Washington
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Being an adult, over the age of 18 years old; Owning diagnosis of breast cancer or head and neck cancer; Being first referred to the radiotherapy protocol; Have integrates skin to start radiotherapy.

Exclusion criteria

Exclusion criteria: Have presented anticipated reaction of hypersensitivity to chamomile or any plant of the family Asteraceae or Compositae.

Design outcomes

Primary

MeasureTime frame
Evaluate the occurrence of erythema, dry desquamation and wet desquamation, according the Acute Radiodermatitis Graduation by Interdisciplinary Laboratory of Oncology Research.

Secondary

MeasureTime frame
Evaluate the subjective symptoms presented by the patients, such as local heat, pruritus, pain, and dry skin according a checklist of subjective symptoms by Interdisciplinary Laboratory of Oncology Research. Evaluate of hydration of the skin by SkinUp – Skin Analyser Digital.

Countries

Brazil

Contacts

Public ContactAmanda de Menêses

Universidade de Brasília

amanda.gdmeneses@gmail.com5561985867107

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 6, 2026