Ischaemic cardiomyopathy.
Conditions
Interventions
60 patients with ischemic cardiomyopathy will undergo myocardial revascularization (saphenous vein surgery). Since the 60 patients will undergo extracorporeal circulation (CPB) during surgery. The CEC
Device
Sponsors
Hospital das Clínicas da Faculdade de Medicina de Botucatu (FMB) da Universidade Estadual Paulista (Unesp)
Universidade Estadual Paulista-Unesp, Faculdade de Medicina de Botucatu.
Eligibility
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Adult patients with coronary artery disease with surgical indication for myocardial revascularization with extracorporeal circulation, aged between 30 and 80 years of age, with and without associated diseases, with people of both sexes.
Exclusion criteria
Exclusion criteria: Adult patients requiring other cardiovascular surgeries (valve, congenital, aortic), coronary artery bypass grafting with associated carotid artery surgery; Anemia prior to surgery; Inflammatory or infectious diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increased hemolysis and inflammatory response in the perioperative period (post-CPB and post-operative 24 hours postoperatively) of myocardial revascularization surgery, using two main types of CPB pumps, verified by the Spearman linear association method from the variation of at least 5% between the changes over the same period | — |
Secondary
| Measure | Time frame |
|---|---|
| Both pumps induced hemolysis and inflammation simultaneously in the post-CPB and 24 hours postoperatively, but without statistical difference (above 5%), and there was a positive association between hemolysis and inflammation for both pumps in the same moments, being the largest these combinations for roller pump. | — |
Countries
Brazil
Contacts
Public ContactAndréia Passaroni
Universidade Estadual Paulista-Unesp, Faculdade de Medicina de Botucatu.
Outcome results
None listed