intestinal constipation
Conditions
Interventions
The study will include 69 patients who underwent surgical treatment for HD with or without the presence of DNI-B, who had been treated for more than 5 years. These patients will be divided into two gr
Other
Sponsors
Faculdade de Medicina de Botucatu - Universidade Estadual Paulista Julio de Mesquita Filho (FMB-UNESP)
Pedro Luiz Toledo de Arruda Lourenção
Eligibility
Age
0 Years to 15 Years
Inclusion criteria
Inclusion criteria: Patients under 15 years at the time of diagnosis and surgical treatment; diagnosis of HD previously established by histopathological analysis of rectal biopsies and confirmed by histopathological analysis of surgical specimens; minimum time of 5 years after surgical treatment; agreement to participate in the study and signing the consent and consent terms.
Exclusion criteria
Exclusion criteria: Aganglionosis region extending beyond the sigmoid colon (long forms of HD); associated diagnosis of other intestinal dysganglionoses, besides HD and DNI-B, in the histopathological analysis of surgical specimens; patients who had perioperative complications, which could potentially influence long-term functional bowel outcomes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in defecation pattern of patients in both study groups, measure by the questionnarie "Bowel Function Score (BF-S). | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in quality of life demonstrated by the PedsQL 4.0 tool in patients in both study groups. | — |
Countries
Brazil
Contacts
Public ContactPedro Luiz Lourenção
Faculdade de Medicina de Botucatu - Universidade Estadual Paulista Julio de Mesquita Filho (FMB-UNESP)
Outcome results
None listed