The role of Melatonin treatment in the Nutritional Health of patients who have had Pineal Gland Cancer

Nutritional assessment of patients with Pineal Tumor before and after Melatonin replacement

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

REBEC

Registry ID

RBR-8z38nht

Enrollment

Unknown

Registered

2025-10-10

Start date

2021-11-22

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pinealectomy

Interventions

Prospective cohort study, with a target sample of 40 patients with pineal gland tumors who underwent different types of treatments (pinealectomy, radiotherapy and/or chemotherapy), of both sexes and o

assessment of the anthropometric profile (weight, height, waist, abdomen, neck and hip circumference) using a scale, stadiometer and tape measure

body composition (% fat mass and % lean mass), assessed by bioelectrical im

D06.472.506

Eligibility

Inclusion criteria

Inclusion criteria: Patients who have undergone surgical treatment for tumors in the pineal region; patients who have undergone chemotherapy for tumors in the pineal region; patients who have undergone radiotherapy for tumors in the pineal region

Exclusion criteria

Exclusion criteria: Current melatonin supplementation; diagnosis of eating disorders; use of appetite suppressants or other medications that chronically alter appetite

Design outcomes

Primary

Measure	Time frame
To evaluate possible changes in the nutritional profile and food consumption due to changes in melatonin production in patients with pineal tumors, through nutritional assessment of the anthropometric profile, body composition, muscle strength and food consumption and comparison of the results with national and/or international reference values ??for age and sex, descriptively defining the adequacy or inadequacy of the parameters.	—

Measure

Time frame

To evaluate possible changes in the nutritional profile and food consumption due to changes in melatonin production in patients with pineal tumors, through nutritional assessment of the anthropometric profile, body composition, muscle strength and food consumption and comparison of the results with national and/or international reference values ??for age and sex, descriptively defining the adequacy or inadequacy of the parameters.

—

Secondary

Measure	Time frame
It is expected to find progressive variations in the nutritional profile and food consumption after melatonin replacement compared to the basal state, through anthropometric assessment, body composition, muscle strength and food consumption, comparing the results found with the respective national and international reference values ??for age and sex to evaluate the effects of melatonin on the progression of the adequacy or inadequacy of these parameters.	—

Measure

Time frame

It is expected to find progressive variations in the nutritional profile and food consumption after melatonin replacement compared to the basal state, through anthropometric assessment, body composition, muscle strength and food consumption, comparing the results found with the respective national and international reference values ??for age and sex to evaluate the effects of melatonin on the progression of the adequacy or inadequacy of these parameters.

—

Countries

Brazil

Contacts

Public ContactNeiva Souza

Universidade Federal de São Paulo

neiva.souza@unifesp.br+55(11)55764848

Outcome results

None listed

Source: REBEC (via WHO ICTRP)