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Effect of Whey Protein Supplementation for Mucositis in BMT Patients

Effect of Food Supplementation with Enriched Milk Protein Concentrate with TGF-ß in reducing oral Mucositis in patients undergoing BMT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8yvd85y
Enrollment
Unknown
Registered
2025-04-07
Start date
2018-01-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stomatitis

Interventions

This is a two-arm, double-blind, randomized controlled clinical trial. Participants were distributed according to a random sequence generated by the Excel program. Group intervention: 20 patients unde
D12.776.256.159.750

Sponsors

Universidade Federal de Juiz de Fora
Lead Sponsor
Hospital Universitário da Universidade Federal de Juiz de Fora
Collaborator

Eligibility

Age
12 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 12 years old; both genders; patients who have not started the conditioning phase

Exclusion criteria

Exclusion criteria: Patients who are allergic to milk proteins; lactose intolerants; suspension of oral nutrition during treatment; death occurring during the data collection period

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: We anticipated finding a higher incidence of oral mucositis in the control group, as assessed by the World Health Organization oral toxicity scale.;Outcome found 1: The control group showed a higher incidence of oral mucositis (65%) compared to the intervention group (40%), as assessed by the World Health Organization oral toxicity scale.

Secondary

MeasureTime frame
Expected outcome 2: We expected to find a higher degree of oral mucositis severity (grade 3 or more, according to the World Health Organization scale) in the control group patients.;Outcome found 2: The control group exhibited a 30% incidence of severe oral mucositis, whereas the intervention group showed a 10% incidence.

Countries

Brazil

Contacts

Public ContactAbrahao Hallack Neto

Hospital Universitário da Universidade Federal de Juiz de Fora

abrahallack@uol.com.br+55(32) 32151523

Outcome results

None listed

Source: REBEC (via WHO ICTRP)