Anal and Perianal Condylomata Acuminata
Conditions
Interventions
Intervention group: 37 patients who underwent the application of argon plasma, until the signs of condylomatous injury were eliminated in an area bounded by a semicircle in anal and perianal region, i
reexamined monthly for six months and made adjuvant operation as required oriented by Proctologic exame.
Control Group: 37 patients treated with electrofulguration until signs of condylomatous lesion
reexamined monthly for six months and made adjuvant operation as required oriented Proctologic exame.
Procedure/surgery
E04.262
Sponsors
Universidade Federal de São Paulo-Escola Paulista de Medicina
Eduardo Angelo Braga
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients older than 18 years were included ; presence of anal HPV , perianal or both , regardless of whether or not they would have been subjected to prior treatment .
Exclusion criteria
Exclusion criteria: We did not include patients with unilateral condylomatous injury or too large for treatment on an outpatient basis and those who did not agree to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The application of argon plasma for the treatment of anal and perianal condyloma would be as effective as electrofulguration. The results were statistically analyzed as fallowing the qualitative variables were described by absolute frequency and percentage and quantitative variables were characterized by mean and standard deviation (SD). To verify association Chi-squared tests asymptotic and exact tests were used. In the analysis of the effectiveness of methods we compare proportions through the Z test and then the Kappa to verify the agreement between the methods. The level of significance was 0.05. The software used was SPSS version 20.0 and Stata 9.1.; The analysis of the number of relapses in relation to application of argon and electrofulguration showed no significant difference with a p-value greater than 0.05. | — |
Secondary
| Measure | Time frame |
|---|---|
| The areas treated with electrofulguration in HIV-positive patients had more relapses than those treated with argon plasma in these same patients. ;After applying the Chi-squared tests asymptotic and exact a 0.05 significance level we find that the number of recurrences in the areas treated with electrofulguration in HIV positive patients was significantly higher with a p value of 0.01. | — |
Countries
Brazil
Contacts
Public ContactEduardo Braga
Universidade Federal de São Paulo-Escola Paulista de Medicina
Outcome results
None listed