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Treatment of dentin hypersensitivity with 5% sodium fluoride varnish, low level laser therapy and associated application: randomized split-mouth clinical study

Treatment of dentin hypersensitivity with 5% sodium fluoride varnish, low level laser therapy and associated application: a clinical, controlled, randomized, split-mouth study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8yq5b8h
Enrollment
Unknown
Registered
2023-09-26
Start date
2017-07-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin Sensitivity

Interventions

This was a randomized, controlled, triple-blind, and split-mouth clinical study. A total of 13 men and women who met the eligibility criteria were chosen to participate. Each participant had four teet

Sponsors

Universidade Estadual Paulista
Lead Sponsor
Universidade Estadual Paulista
Collaborator

Eligibility

Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers; male or female aged between 20 and 65 years; with healthy periodontium; no periodontitis or gingivitis; presenting teeth without the presence of caries, cracks, fractures or extensive restorations; presenting teeth without premature contact; volunteers who have understood the study design; volunteers who have at least four sensitive teeth in their mouths, one in each oral quadrant; volunteers who have signed and agreed to the Informed Consent Form

Exclusion criteria

Exclusion criteria: Pregnant or breastfeeding women; subjects registered in another clinical trial; individuals who underwent professional treatment for hypersensitivity, or who used desensitizing products in the 3 months preceding the research period; history of maxillofacial cancer in the last 5 years; need for systemic treatment due to infection; patients who make chronic use of anti-inflammatory drugs, analgesics or psychotropic drugs; individuals who have allergies or who have some idiosyncratic response to any component of the product used in the research; patients who present parafunctional habits, eating disorders, gastric or emotional illness that is predisposed to dentin sensitivity; advanced medical or psychological illness; alcohol consumption or drug intoxication; hemorrhagic disease; systemic condition that is an etiological or predisposing factor for dentin sensitivity; diet with excessive exposure to acidic foods; individuals who underwent periodontal surgery or orthodontic treatment in the preceding 3 months; dental or periodontal pathologies, or defects that cause pain, such as caries, “brackets”, and extensive fillings; teeth that serve as "abutments" or support for fixed or removable dentures, or that have crowns; teeth with restorations that extend to the test area (cervical); teeth with irreversible pulp inflammation.

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: It is expected to find an improvement in dentin sensitivity, assessed by the VAS scale, the study's primary variable, in the 5% Sodium Fluoride group associated with Low Power Laser Therapy (F+LLLT) after 24 and 30 hours. 90 and 180 days.;Outcome found 1: Through the evaluation of the VAS pain scale, an improvement in dentin sensitivity was observed, it was observed that therapy (F) demonstrated the greatest reduction in hypersensitivity in 180 days, this being considered the therapy with the greatest effectiveness and effect lasting in the medium term.

Secondary

MeasureTime frame
It was not expected or evaluated.

Countries

Brazil

Contacts

Public ContactAndrea De Marco

Universidade Estadual Paulista

andrea.marco@unesp.br+55(12)39479323

Outcome results

None listed

Source: REBEC (via WHO ICTRP)