Chronic kidney disease, hemodialysis
Conditions
Interventions
Group 1: 7 patients on maintenance hemodialysis that will receive Cholecalciferol (vitamin D) suplementation, dose of 50000 UI, once a week for 4 months, capsule orally,and aerobic exercise training o
Group 2: 7 patients on maintenance hemodialysis that will receive orally a capsule of placebo once a week for 4 months, and aerobic exercise training on exercise bike (30 minutes three times a week fo
Group 3: 7 patients on maintenance hemodialysis that will receive Cholecalciferol (vitamin D) suplementation, dose of 50000 UI, once a week for 4 months, capsule orally,and will not realize aerobic ex
Group 4: 7 patients on maintenance hemodialysis that will receive orally a capsule of placebo once a week for 4 months, and will not realize aerobic exercise training.
Other
I02.233.543
Sponsors
Faculdade de Medicina de Botucatu
Hospital das Clínicas da Faculdade de Medicina de Botucatu
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Individuals older than 18 years; with chronic kidney disease on dialysis for a period greater than or equal to three months; classified as sedentary or irregularly active according to the International Physical Activity Questionnaire (IPAQ); do not have contraindications to physical activity; and accept and sign the Informed Consent.
Exclusion criteria
Exclusion criteria: Individuals unable to understand the procedures performed; prior diagnosis of coronary artery disease; positive exercise test for cardiac ischemia; patients classified as active or very active based on the International Physical Activity Questionnaire; Patients who have suffered stroke; patients with cancer, liver failure, chronic infection or acute in activity; uncontrolled hypertension (> 160 mmHg systolic or > 100 mmHg diastolic); Use of medications that affect body composition, such as corticosteroids and antiretroviral therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant increase in total muscle mass in the assessment before and after intervention period assessed by X-ray absorptiometry dual energy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Significant increase in lower limbs muscle mass in the assessment before and after intervention period assessed by X-ray absorptiometry dual energy. ;Significant increase of overall muscle function in the assessment before and after intervention period assessed by handgrip strength. | — |
Countries
Brazil
Contacts
Public ContactJacqueline Caramori
Faculdade de Medicina de Botucatu
Outcome results
None listed