Alopecia
Conditions
Interventions
This is a randomized, single-center, double-blinded trial with a 24-week longitudinal follow-up. A total of 30 patients who meet the eligibility criteria will be randomly divided into two groups of 15
Sponsors
Clinica Sanabria Transplante e Restauração Capilar
Hospital Universitário Maria Aparecida Pedrossian da Universidade Federal do Mato Grosso do Sul
Eligibility
Sex/Gender
Male
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Males; Age between 20 and 60 years; Diagnosis of Androgenetic Alopecia grades 3V, 4V or 5V on the Norwood-Hamilton scale
Exclusion criteria
Exclusion criteria: Patients who have undergone hair loss treatment in the last 4 months; those with systemic arterial hypertension; heart disease; kidney disease; those with other causes of hair loss or scalp dermatoses
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: An increase in the density of terminal hairs in the target area is expected, greater in the group using dutasteride 0.2% compared to the group with 0.1%, assessed by comparing the trichoscopic photography performed before treatment and repeated after 24 weeks, in the vertex region using FotoFinder equipment and analysis and counting of the total number of hairs using Tricholab software, with long hair. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: An increase in the density of total hairs in the target area is expected, greater in the group using dutasteride 0.2% compared to the group with 0.1%, assessed by comparing the trichoscopic photography performed before treatment and repeated after 24 weeks, in the vertex region using FotoFinder equipment and analysis and counting of the total number of hairs using Tricholab software, with long hair.;Expected outcome 3: Overall hair coverage is expected to improve more in the dutasteride 0.2% group than in the dutasteride 0.1% group, as assessed by comparing standardized clinical photographs taken pre-treatment and after 24 weeks, with patients being asked to maintain the same hair style, color, length, and cut throughout the study. The standardized photographs were evaluated by 3 dermatologists who were blinded to treatment. Each dermatologist compared the baseline photograph with the photograph after 24 weeks of treatment and used a 7-point comparison scale: marked worsening (-3), moderate worsening (-2), slight worsening (-1), no change (0), slight improvement (+1), moderate improvement (+2), and marked improvement (+3). | — |
Countries
Brazil
Contacts
Public ContactMarcelo Medeiros
Clinica Sanabria Transplante e Restauração Capilar
Outcome results
None listed