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Evaluation of the use of isotonic serum in patients admitted to Pediatric Intensive Care

Evaluation of the use of isotonic serum in patients admitted to Pediatric Intensive Care

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8ybbm9
Enrollment
Unknown
Registered
2019-01-07
Start date
2017-04-04
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Water overload in critically ill patients

Interventions

The daily recommended water supply for children who require maintenance hydration is 100 ml / kcal / day of isotonic solution. The intervention was performed in the study group that received the restr
Other

Sponsors

Complexo Hospital de Clínicas Universidade Federal do Paraná
Lead Sponsor
Complexo Hospital de Clínicas Universidade Federal do Paraná
Collaborator

Eligibility

Age
28 Days to 15 Years

Inclusion criteria

Inclusion criteria: Patients of both sexes admitted to the Pediatric Intensive Care Unit of the Hospital de Clínicas Complex of the Federal University of Paraná, Brazil who signed a free and informed consent form, were included.

Exclusion criteria

Exclusion criteria: Patients with dialysis renal insufficiency; diabetic ketoacidosis; sickle cell anemia; hypernatremia with sodium above 170mEq / L; patients who did not require a basic maintenance plan or who remained less than 24 hours in the Pediatric Intensive Care unit were excluded from the study.

Design outcomes

Primary

MeasureTime frame
The isotonic solution with the infusion rate of 100ml / kcal / day as daily fluid maintenance of critically ill patients admitted to the Pediatric Intensive Care Unit of the Hospital de Clínicas Complex of the Federal University of Paraná, during the first 72h of hospitalization, increases the overload when compared to infusion rate of isotonic solution of 60ml / kcal / day. The overload will be evaluated by the formula: (Input Fluid - Output Output) / Input Weight x 100 =% Water Overload. Results above 5% will be considered water overload.

Secondary

MeasureTime frame
Presence of hyperchloremic metabolic acidosis with 0.9% saline solution as maintenance isotonic fluid in the control group.

Countries

Brazil

Contacts

Public ContactMariana Pechebea

Complexo Hospital de Clínicas Universidade Federal do Paraná

madigiovanni@gmail.com+55-041-999217789

Outcome results

None listed

Source: REBEC (via WHO ICTRP)