Chronic Kidney Disease-Mineral and Bone Disorder
Conditions
Interventions
This is a randomized, controlled, and blinded clinical trial with allocation concealment. Five researchers will participate in the study: one will be responsible for randomization and blinding, two wi
however, evaluations and load adjustments will require the patient to attend the facility once a week. Home sessions will be recorded in a diary provided on the first day of training.The protocol will
E02.190.525.186
Sponsors
Centro de Ciências da Saúde (CCS)
Centro de Ciências da Saúde (CCS)
Eligibility
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with a clinical diagnosis of Chronic Kidney Disease (CKD) in the non-dialytic stage, according to the criteria established by the National Kidney Foundation; aged between 40 and 70 years; male and female patients; clinically stable; without recent episodes of acute decompensation; capable of understanding and performing the maneuvers required for inspiratory muscle training (IMT).
Exclusion criteria
Exclusion criteria: Patients undergoing renal replacement therapy (hemodialysis; peritoneal dialysis; or kidney transplant); those presenting with acute or chronic respiratory diseases; neurological or musculoskeletal conditions that interfere with the performance of respiratory exercises; cognitive or behavioral incapacity that prevents participation in the study or adherence to the protocol instructions; or any other medical condition that renders the patient ineligible to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find an increase in inspiratory muscle strength after the inspiratory muscle training protocol, verified by means of digital manovacuometry, based on the observation of a variation of at least 10% in relation to pre-intervention measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| An increase in diaphragmatic mobility is expected, as verified by ultrasound of the diaphragm muscle, with a minimum variation of 5 mm in relation to the baseline. ;It is expected to identify an increase in the thickness of the diaphragm muscle during inspiration, verified by ultrasound, considering a variation greater than 10% compared to initial measurements. | — |
Countries
Brazil
Contacts
Public ContactTiago de Macêdo
Universidade Federal de Pernambuco Campus Recife
Outcome results
None listed