Prevention of postoperative nausea, vomiting and pain in patient undergoing breast reconstruction after bariatric surgery.
Conditions
Interventions
Administration of 75mg of pregabalin in 26 patients undergoing breast reconstruction after bariatric surgery or placebo in 26 patients undergoing breast reconstruction after bariatric surgery, orally,
Sponsors
Rafael Reis Fernandes
Rafael Reis Fernandes
Eligibility
Sex/Gender
Female
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Female gender; age between eighteen and sixty-four years; physical state classified by the American Society of Anesthesiology scale one and two; breast reconstruction surgery after bariatric surgery.
Exclusion criteria
Exclusion criteria: Volunteers with participation in another study in the last month; smokers and alcoholics; body mass index greater than thirty-five kg / m2; occurrence of episodes of nausea or vomiting in the last twenty-four hours preceding the surgery; use of corticosteroids, use of psychoactive drugs or any medication with antiemetic effect; known hypersensitivity to any study medication; volunteers with severe kidney, liver, lung, heart, brain and bone marrow diseases; volunteers who had a history of postoperative vomiting or unavoidable vomiting even after the administration of rescue medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the antiemetic, effect through the use of pregabalin or placebo, to observe the frequency and intensity of individual episodes of nausea and the frequency of vomiting, in the first 24 postoperative hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate the analgesic effect, using pregabalin or placebo, to observe the frequency, intensity and characteristics of postoperative pain.;Assess the incidence of adverse effects due to the use of pregabalin.;To assess the incidence of chronic pain, using pregabalin or placebo, in the late postoperative period of 3 months. | — |
Countries
Brazil
Contacts
Public ContactRafael Fernandes
Outcome results
None listed