Systemic sclerosis
Conditions
Interventions
Participants will be randomized in 4 blocks of 4 participants into 2 groups (moderate-intensity resistance training (MIT) and home training (HT)). The researchers responsible for patient assessment an
E02.760.169.063.500.387.875
Sponsors
Hospital de Clínicas de Porto Alegre
Eligibility
Sex/Gender
Female
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: Women; minimum age 45 years; diagnosis of Systemic Sclerosis according to the American College of Rheumatology
Exclusion criteria
Exclusion criteria: Overlapping autoimmune diseases, except sjögren syndrom; use of ergogenic resources; uncontrolled heart or circulatory disease; palpitation; pulmonary artery systolic pressure (PASP) > 35mmHg; forced vital capacity (FVC) < 70% of estimated; inability to adhere to home-based training; inability to understand and sign the informed consent form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find an increase in muscle strength after 12 weeks of resistance training, evaluated by the method of 1 maximum repetition for the knee extension exercise, with a difference of 3.14(1.9)kg between the resistance training moderate intensity and home based training groups . | — |
Secondary
| Measure | Time frame |
|---|---|
| We expect to find an increase in muscle quantity and improvement in muscle quality, as assessed by dual-energy x-ray absopciometry (DXA) and ultrasonography, respectively. This improvement should occur in both groups, but will be greater in the RT-MI group.;We expect to find an improvement in physical performance evaluated through the short physical performance battery (SPPB), Timed Up and Go (TUG) tools and the 30-second sit-to-stand test;It is believed that there will be superior adherence to treatment in the TR-MI group when compared to the TD group. This will be evaluated through the records of presence in the RT-MI group and the training diary, which appears in the participant's handout, delivered to the participants of the HBT group. | — |
Countries
Brazil
Contacts
Public ContactAndré Mallmann
Hospital de Clínicas de Porto Alegre da Universidade Federal do Rio Grade do Sul
Outcome results
None listed