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Low sugar diet combined with nasal administration of perillyl alcohol: strategy therapy for resistant Glioblastoma Multiforme to chemotherapy and radiotherapy

Ketogenic diet combined with intranasal administration of perillyl alcohol: strategy therapy to refractory Glioblastoma Multiforme to standard treatment

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8x8fd9
Enrollment
Unknown
Registered
2016-07-21
Start date
2015-10-05
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioblastoma multiforme. Malignant gliomas.

Interventions

Group 1 (intervention), 15 patients, will be made anthropometric measurements, biochemical tests, MRI, demographic and social data will be collected and ketogenic diet will be offered. They will be f
Other
C04.557.465.625.600.380.080.335

Sponsors

Hospital Universitário Antônio Pedro
Lead Sponsor
Hospital Universitário Antônio Pedro
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Men and women with recurrent glioblastoma multiforme; aged 20 to 65; standard therapy (chemotherapy and/or radiotherapy); inhalating perillyl alcohol.

Exclusion criteria

Exclusion criteria: Patients with neurological complications; terminal phase; discontinue diet.

Design outcomes

Primary

MeasureTime frame
Comparison of tumor growth by anterior cerebral magnetic resonance imaging at baseline and after 3 months of combined therapy with inhalation of perillil alcohol and ketogenic diet.—

Secondary

MeasureTime frame
Changes in body composition checked by anthropometric measurements before and after dietotherapeutic intervention.—

Countries

Brazil

Contacts

Public ContactClóvis Pereira da Fonseca

Universidade Federal Fluminense

clovis.orlando@uol.com.br+55 (21) 2629 9000

Outcome results

None listed

Source: REBEC (via WHO ICTRP)