metabolic syndrome
Conditions
Interventions
This is a two-arm, single-blinded randomized controlled clinical trial (n=50). Experimental group: 25 adult individuals with metabolic syndrome will receive jabuticaba bark supplement 15g/day for 5 we
G07.203.300.456
Sponsors
Faculdade de Engenharia de Alimentos
Universidade Estadual de Campinas
Eligibility
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: men and women; ity between 18 and 60 years; diagnosed with metabolic syndrome, with =3 components Metabolic syndrome, or seja, altered jejum glycemia (= 100 mg/dL), hypertension (systolic blood pressure = 130 mm Hg or diastolic blood pressure = 85 mm Hg), central adiposity (circumference abdominal = 88 cm for women and = 102 cm for men), hypertriglyceridemia (= 150 mg/dL) and low levels of HDL cholesterol (<40 mg/dL in women and <50 mg/dL in men).
Exclusion criteria
Exclusion criteria: Taking oral hypoglycemic agents; with food allergy, hypersensitivity or intolerance; smokers; vegetarians or vegans; diabetes, individuals who have been taking vitamins, probiotics and dietary supplements for the past 3 months; women in pregnancy or breastfeeding; clinical or laboratory evidence of renal, hepatic, intestinal, cardiac or other serious systemic disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find improvement in GLP-1 by ELISA kit from statistical analysis using SPSS software adopting the significance value of 5%. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find improvement in insulin sensitivity is expected in patients treated with jabuticaba peel poder assessed by HOMA-IR, Oral Glucose Insulin Sensitivity (OGIS), beta cell sensitivity to glucose and insulin rate sensitivity, from statistical analysis using SPSS software adopting the significance value of 5%.;It is expected to find improvement in the inflammatory profile assessed by the quantification of interleukin 6, interleukin 1B, tumor necrosis factor alpha, and C-reactive pretein from statistical analysis using SPSS software adopting the significance value of 5%.;It is expected to find improvement in the lipid profile through the reduction of total cholesterol and triglycerides and increase of HDL from statistical analysis using the SPSS Software adopting the significance value of 5%. | — |
Countries
Brazil
Contacts
Public ContactMário;Marina Maróstica Júnior;Vilar Geraldi
Universidade Estadual de Campinas;Universidade Estadual de Campinas
Outcome results
None listed