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The effect of medications to combat the generated sensitivity after the tooth whitening office

Effectiveness of two drugs in controlling sensitivity generated by office tooth whitening: A clinical, randomized, blinded trial - : Effectiveness of the associated drugs or not a desensitizing the control of sensitivity generated by tooth whitening office

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8w369s
Enrollment
Unknown
Registered
2016-01-19
Start date
2016-01-09
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tooth sensitivity, transitory toothache

Interventions

Patients will be randomly selected and divided form in 7 groups of 10 patients each: * G1: Control group with whitened teeth without desensitizing nano p
no placebo intake and using ordinary toothpaste (brushing for 21 days: 7 days before and 14 after the bleaching treatment) * G2: Group with whitened teeth without desensitizing nano p
and using toothpaste Colgate Pro-Relief (brushing for 21 days: 7 days before and 14 after the bleaching treatment)
* G3: Control group with whitened teeth without desensitizing nano p
and placebo ingestion (taking 1 hour before bleaching treatment and standing for 3 days)
* G4: Group with whitened teeth without desensitizing nano p
ibuprofen 400mg intake (taking 1 hour before bleaching treatment and standing for 3 days)
* G5: Group with teeth whitened with desensitizing nano p with ibuprofen 400mg intake (take 1 hour before the bleaching treatment and staying for 3 days)
* G6: Group with whitened teeth without desensitizing nano p with codeine intake 30mg (take 1 hour before the bleaching treatment and staying for 3 days)
G7 *: Group with desensitizing teeth bleached with nano w, 30mg codeine intake (taking 1 hour before bleaching treatment and standing for 3 days).
Drug

Sponsors

Universidade Federal do Rio Grande do Norte
Lead Sponsor
Universidade Federal do Rio Grande do Norte
Collaborator

Eligibility

Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Individuals must be at least 18 years old, doesn't have hipersenssibilidade to ibuprofen and codeine; be nonsmoking; have teeth with greater color A2; possess good oral and general health; have front teeth upper and lower vital; free of cavities or restorations without cervical lesions and without periodontal disease.

Exclusion criteria

Exclusion criteria: Pregnant women will be excluded or breastfeeding; people with discolored teeth caused by tetracycline; with fluorosis; hyperplasia; endodontic treatment or needing root canal treatment; and parafunctional habits. People who have any condition that may cause sensitivity such as recession or exposure of dentin are excluded from this study to minimize confusion of experimental variables or side effects of bleaching. Participants who report a health problem history in the stomach; heart; kidney; or liver or participants using any continuous drug with anti inflammatory action are also excluded from the study.

Design outcomes

Primary

MeasureTime frame
The association of analgesic and anti-inflammatory drugs; with or without desensitizing does reduce or eliminate the sensitivity generated by the office tooth bleaching. Will be evaluated after the verification of the data distribution (Kolmogorov-Smirnov test). Later, you run a parametric or non-parametric test followed by an appropriate post-test.

Secondary

MeasureTime frame
Secondary outcomes are not expected.

Countries

Brazil

Contacts

Public Contactsamila de oliveira

Universidade Federal do Rio Grande do Norte

samilaoliveira18@hotmail.com+55(84) 996492359

Outcome results

None listed

Source: REBEC (via WHO ICTRP)