Effect of Ibuprofen and Arginine gel on sensitivity after whitening: controlled clinical study

Desensitizing action of topical application of Ibuprofen and Arginine gel on post-whitening sensitivity: a randomized, double-blind, split-mouth clinical study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

REBEC

Registry ID

RBR-8skkj7q

Enrollment

Unknown

Registered

2025-05-05

Start date

2025-01-01

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dental sensitivity

Interventions

A controlled, randomized, double-blind clinical trial will be conducted to evaluate the efficacy of a desensitizing gel after dental whitening with a total of 30 people who meet the eligibility criter

E06.342.377

Eligibility

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Patients of both sexes; aged between 18 and 30 years; presence of all vital anterior teeth; never having undergone dental whitening; not having restored anterior teeth; not having central incisor teeth with color A2 or darker

Exclusion criteria

Exclusion criteria: Patients with missing front teeth; with caries lesions; presence of gingival recession; with any restorative or prosthetic treatments; history of dental hypersensitivity; dental discoloration due to Tetracycline or Fluorosis; who use continuous medications such as anti-inflammatories and analgesics; pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
It is expected to find a notable reduction in dentin sensitivity during and after dental whitening, improving the patient's experience of dental whitening	—

Secondary

Measure	Time frame
No secondary outcome	—

Countries

Brazil

Contacts

Public Contactsuelen dalagustinho

União Educacional de Cascavel

suelenkauana@icloud.com+55(45)991051230

Outcome results

None listed

Source: REBEC (via WHO ICTRP)