Periodontal disease
Conditions
Interventions
60 periodontally health women, between 18-40 years old, will be evaluated in a observational study. These patients will include 15 smoking women, 15 pregnant women in the 3rd trimester of pregnancy, 1
V03.175.500
Sponsors
Faculdade São Leopoldo Mandic
Faculdade São Leopoldo Mandic
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Women between 18 and 40 years old; At least 20 teeth in the mouth; Absence of periodontitis (periodontal pocket greater than 4mm accompanied by proximal bone loss); Each group will include: - G1: pregnant smokers (n = 15); - G2: non-smoking pregnant women (n = 15); - G3: non-pregnant smokers (n = 15); - G4: non-pregnant non-smokers (n = 15); To be included in the G1 or G2 group, pregnant women must be in the third trimester (28 to 40 weeks) of pregnancy and undergo medical and prenatal care every 4 weeks at the health post; In G3 or G4: non-pregnant woman; to be included in G1 and G3 to be a regular smoker (smoker with a consumption of more than 10 cigarettes / day).
Exclusion criteria
Exclusion criteria: Presence of systemic disorders reported in the initial anamnesis and in the medical record of prenatal care of the patient at the health center; use of antibiotics 6 months prior to the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in the subgingival biofilm microbial community between groups, assessed by metrics of alpha and beta diversity and compared by statistical tests considering an alpha = 5%. | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in probing depth (measurement of the distance from the gingival margin to the clinically detectable base of the groove / periodontal pocket) between groups, measured using the millimeter probe at the time of clinical evaluation, and compared by statistical tests considering an alpha = 5%.;Differences in bleeding on probing (measurement of gingival bleeding after periodontal probing) between groups, assessing the presence or absence of bleeding, and compared by statistical tests considering an alpha = 5%. | — |
Countries
Brazil
Contacts
Public ContactJulio Joly
Faculdade São Leopoldo Mandic
Outcome results
None listed