Skip to content

Analysis of different sealers used in root canal treatment on postoperative pain in endodontics.

Effect of calcium silicate-based sealer and epoxic resin-based sealer on post-operative pain in endodontics: a randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
REBEC
Registry ID
RBR-8s5cbfk
Enrollment
Unknown
Registered
2022-03-08
Start date
2021-12-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulpitis

Interventions

Experimental group: 50 healthy adults with pulpitis in permanent molars will undergo endodontic treatment with a reciprocating system in a single visit and the sealer used will be based on calcium sil
E06.397.778

Sponsors

Universidade Federal do Amazonas
Lead Sponsor
Universidade Federal do Amazonas
Collaborator

Eligibility

Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Men and women aged 18–65 years, diagnosed with symptomatic irreversible pulpitis with indication for endodontic treatment in permanent molar teeth, will be included in the study, confirmed by positive response to clinical, cold vitality and radiographic tests. The individual who participates in this research must have a contact number (phone or cell phone) to be able to carry out the post-operative evaluations.

Exclusion criteria

Exclusion criteria: Patients who were pregnant, immunocompromised, on medication or hypersensitive to anti-inflammatory drugs, or patients with occlusal disorders or any type of periodontitis or endodontic complications were excluded from the study, since these conditions would interfere with the analysis of the presence of pain after endodontic treatment.

Design outcomes

Primary

MeasureTime frame
To evaluate the prevalence of postoperative pain after endodontic treatment in patients participating in the research in a period of 6, 12, 24, 48 and 72 hours and its intensity using a validated pain scale NRS type with a score of zero (no pain) up to 10 cm (maximum pain).

Secondary

MeasureTime frame
The secondary outcomes will be worked with the statistical analysis of regression to verify if the occurrence of postoperative pain of the primary outcome could be being influenced by the possible accidental cases of overfilling or by the need of administration of rescue medication among the participants of the groups.

Countries

Brazil

Contacts

Public ContactEmílio Sponchiado Junior

Universidade Federal do Amazonas

spemilio@ufam.edu.br+55(92)33054908

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Apr 4, 2026