Inflammatory Manifestations in the Extraction of Impacted Lower Third Molars.
Conditions
Interventions
This is a two-arm, double-blind, randomized controlled clinical trial. The sample will consist of 64 participants, totaling 128 surgeries. All extractions will be performed by one oral and maxillofaci
Sponsors
Universidade de São Paulo
Universidade de São Paulo
Eligibility
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Eligibility criteria will include participants who: are between 18 and 40 years old, are not pregnant, require bilateral extraction of lower third molars with a similar degree of bone impaction, have no systemic diseases or local conditions that could interfere with the tissue repair process, undergo a surgical procedure lasting up to 60 minutes, have no contraindications to the use of hydrocortisone, have no history of hypersensitivity to mepivacaine, dipyrone, and ibuprofen, have the presence of upper and lower central incisors, and have no light hypersensitivity
Exclusion criteria
Exclusion criteria: Exclusion criteria will include participants under 18 or over 40 years of age, participants who are pregnant, procedures that exceed 60 minutes in duration, trans-surgical complications (e.g., hemorrhage or fainting), participants who do not follow up within the proposed interval or do not return for the second extraction, participants who report using medications other than those provided by the research team, use of anesthetics exceeding the amount outlined in this study (2 cartridges), as well as the absence of upper and lower central incisors, a history of hypersensitivity to mepivacaine, dipyrone, and ibuprofen, and light hypersensitivity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate whether the exclusive use of postoperative photobiomodulation therapy, after extraction of impacted lower third molars, by analyzing the limitation of mouth opening, has an anti-inflammatory effect equal to or superior to the use of hydrocortisone | — |
Secondary
| Measure | Time frame |
|---|---|
| To comparatively evaluate the postoperative edema following the extraction of impacted lower third molars in patients who underwent intraoperative hydrocortisone wound irrigation and postoperative photobiomodulation therapy versus patients who underwent exclusive postoperative photobiomodulation therapy;To comparatively evaluate postoperative pain following the extraction of impacted lower third molars in patients who underwent intraoperative hydrocortisone wound irrigation and postoperative photobiomodulation therapy versus patients who underwent exclusive postoperative photobiomodulation therapy | — |
Countries
Brazil
Contacts
Public ContactLaís Fernandes
Universidade de São Paulo
Outcome results
None listed