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Evaluation of the use of Cannabidiol in Third Molar Extraction

Evaluation of the use of Cannabidiol in Third Molar Extraction Surgeries

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
REBEC
Registry ID
RBR-8rv93wn
Enrollment
Unknown
Registered
2023-10-17
Start date
2024-01-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Management

Interventions

This is a randomized, controlled clinical trial in a parallel, and double-blind model. The evaluating researchers and the participants will not know which group each participant belongs. Forty patient
CTR: Use of placebo oil starting at the time of the surgical procedure and for 5 days after the surgical procedure. Patients will be clinically analyzed in periods of 3, 7, 15 and 30 days after tooth

Sponsors

Universidade Federal de Uberlândia
Lead Sponsor
Universidade Federal de Uberlândia
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients of both genders. aged between 18 and 60 years. who are systemically healthy and who require surgery to remove the four third molars

Exclusion criteria

Exclusion criteria: Patients using drugs acting on the central nervous system. decompensated diabetics (glycated hemoglobin above 8%). consumption of any medication 15 days prior to inclusion in this study, patients with hypersensitivity to the drugs to be used in postoperative care, pregnant women or during lactation. chronic smokers and alcoholics. presence of periapical lesions. presence of pericoronitis lesions

Design outcomes

Primary

MeasureTime frame
The use of cannabinoid will reduce the painful sensation by 2 points on the visual analogue pain perception scale and will reduce the consumption of analgesics and anti-inflammatories by 10% in the postoperative phase of third molar extractions compared to the placebo group.

Secondary

MeasureTime frame
The use of cannabinoid will reduce edema by 10%, and will improve soft tissue healing by 10% in the postoperative phase of third molar extractions compared to the placebo group.

Countries

Brazil

Contacts

Public ContactGuilherme Oliveira

Universidade Federal de Uberlândia

guilherme.lopesoliveira@ufu.br+55(34)32258132

Outcome results

None listed

Source: REBEC (via WHO ICTRP)