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The Effectiveness of Strengthening Respiratory Muscles and their Relationship with Fatigue in Patients with Multiple Sclerosis

The Effects of Respiratory Muscle Strengthening in relation to Pulmonary Fatigue in Patients with Multiple Sclerosis and with Hypovitaminosis D

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8rkrr3
Enrollment
Unknown
Registered
2020-03-31
Start date
2016-01-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis.

Interventions

Group A (n = 10): the patients in the treatment group will recieve respiratory muscle training using the Power Breathe Plus Light Resistance model. The strength training will start with two sets of 10
Other
E02.190.525.186

Sponsors

Faculdade de Medicina da Universidade Federal de Goiás
Lead Sponsor
Faculdade de Fisioterapia da Universidade Estadual de Goiás
Collaborator

Eligibility

Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with clinical diagnosis of Multiple Sclerosis in remitting-recurrent form according to the revised McDonald criteria; EDSS (Expanded Disability Status Scale) up to 6.0 according to the Kurtzke scale; Stable phase of the disease (after any 30 days of the outbreak); Orbicular strenght of the lips sufficient to support the mouthpiece during respiratory assessment.

Exclusion criteria

Exclusion criteria: Any neurological disorder other than Multiple Sclerosis; History of primary cardiopulmonary diseases; Difficulty to understand simple instructions.

Design outcomes

Primary

MeasureTime frame
Fatigue: will be assessed using the Fatigue Severity Scale, which consists of a numerical scale composed of 9 questions with scores ranging from 1 to 7 each, where 1 represents strong disagreement and 7 maximum agreement. Values above 28 points can be considered as indicators of the presence of fatigue. The Chalder Fatigue Scale will also be used, which contains 11 items with scores from 0 to 3 each, where the values 0 and 1 are considered as zero and the values 2 and 3 as one. The sum of the values greater than or equal to 4 characterizes the presence of fatigue. Fatigue will be evaluated before and after the intervention. ;Strength: will be assessed by means of manovacuometry, which consists of measuring MIP and MEP at the level of functional lung capacity and residual volume. Indexes less than - 70 cmH2o of MIP and less than 95 cmH2o of MEP characterize the degree of weakness. Strength will be evaluated before and after the intervention.

Secondary

MeasureTime frame
Dynamic respiratory function: it will be evaluated by means of spirometry, where the variables analyzed will be the forced vital capacity, the forced expiratory volume and the peak expiratory flow. Respiratory function will be assessed before and after the intervention.;International Classification of Functionality and Disability: will be used to describe the muscular fatigue of the evaluated patients.

Countries

Brazil

Contacts

Public ContactAmanda Rodrigues

Faculdade de Medicina da Universidade Federal de Goiás

amandaelrodri@hotmail.com+55-062-981326497

Outcome results

None listed

Source: REBEC (via WHO ICTRP)