Tooth Extraction
Conditions
Interventions
After selection, the patients were divided into three groups according to the orally administered preoperative medication: 1 - DEX 8 mg (Laboratório Teuto Brasileiro s/a – 17159229000176, Brazil, Anáp
Drug
Procedure/surgery
Q65.070
Sponsors
Faculdade de Odontologia campus de Araçatuba unesp
Faculdade de Odontologia campus de Araçatuba unesp
Eligibility
Age
16 Years to 35 Years
Inclusion criteria
Inclusion criteria: Participants met the inclusion criteria determined by means of anamnesis, clinical, and radiographic examinations. Included patients comprised those in good systemic and general health condition, between 16 and 35 years of age, and those with an indication of lower third molar (#38 or 48) removal, with at least 2/3 of the root formed, according to the radiographic evaluation (Class I or II; Position A/B from Pell & Gregory, 1942).
Exclusion criteria
Exclusion criteria: Participant exclusion criteria was also obtained by means of anamnesis, clinical, and radiographic examinations 6- 8- 9- 11- 14- 23- 24; they included all the opposite questions regarding the inclusion criteria plus the individuals who used any drug in the 30 days prior to the surgical procedure, and female patients during menstrual, gestational, or lactation periods.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study aimed to evaluate the effect of preemptive analgesia between the association of non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids and the use of corticosteroids alone, after extraction of third molars. It is expected that the association of the two types of anti-inflammatory drugs (NSAIDs and corticosteroids) will be able to reduce postoperative pain, assessed by analogue visual scale (VAS) analysis in periods of 6, 12, 24, 48, 72 hours and 7 days, in which the patient reports the sensation of postoperative pain choosing a value for the sensation of 0 to 10 in a subjective spectrum. Postoperative pain will also be assessed using the number of rescue analgesics consumed, which represents the amount of analgesics the patient reported need to consume according to the pain they felt. It is also expected that the combination of anti-inflammatories will reduce postoperative edema, which will be evaluated by measuring craniometric points related to edema in the 48-hour and 7-day periods. The reduction of postoperative trismus is also expected from the association of anti-inflammatory drugs. This parameter will be evaluated through the linear measurement of the patient's oral opening, represented by the interincisal distance of the patient.;Outcomes found: With regard to postoperative pain, it was possible to observe that the association between anti-inflammatory drugs (NSAIDs and corticosteroids) reduced postoperative pain related to analysis through the visual analogue scale, as well as, reduced the consumption of analgesics of rescue in the postoperative period. Edema also showed reduction in all periods for the association of anti-inflammatories. However, trismus did not present the expected outcome, remaining at higher values ??for the association of anti-inflammatory drugs | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected. | — |
Countries
Brazil
Contacts
Public ContactFabio Miranda
Faculdade de Odontologia campus de Araçatuba unesp
Outcome results
None listed