Chronic Renal Failure, dialysis.
Conditions
Interventions
After signing the informed consent form, the subjects were randomized according to sex, age, and protein intake using the protein equivalent of Nitrogen (NAP) and divided into two groups: Control Grou
Dietary supplement
SP6.051.227
Sponsors
Faculdade de Nutrição da Universidade Federal de Goiás
Centro de Nefrologia - Centrel
Faculdade de Nutrição da Universidade Federal de Goiás
Eligibility
Age
20 Years to 79 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria adopted for participation in the study were: patients of both sexes, aged between 20 and 79 years, for at least three months on hemodialysis treatment, performing three sessions per week.
Exclusion criteria
Exclusion criteria: The exclusion criteria were: bedridden patients; Amputees; Patients with decompensated diabetes; Pregnant women; Who are consuming nutritional supplements containing protein; Food intolerance or allergy to egg white protein; Liver disease, intestinal malabsorption, cancer and Acquired Immunodeficiency Syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of body composition with preservation of muscle mass, assessed by electrical bioimpedance. Outcomes were assessed 1 week before and after the intervention. The statistical power associated to the sample size estimated by the mean of the difference in muscle mass of 20 patients from the control (pilot) group was calculated. The sample calculation was estimated in 24 participants, with a level of significance of 5% and statistical power of 80% for a difference of 0.5 kg in muscle mass as significant.;The intervention had no effect on muscle mass (p=0.351). | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of inflammatory markers, evaluated by biochemical tests of C-reactive protein (CRP) and Interleukin 6 (IL-6). Outcomes were assessed 1 week before and after the intervention. Increased quality of life, assessed by means of the questionnaire of specific quality of life for chronic kidney disease. Outcomes were assessed 15 days before and after the intervention.;Analysis of the inflammatory markers will still be performed.;Protein supplementation improved the dimension of "symptoms and problems" related to CKD, of the quality of life questionnaire (p=0.028). | — |
Countries
Brazil
Contacts
Public ContactGleicy;Maria Fernandes Nunes;Gondim Peixoto
Faculdade de Nutrição da Universidade Federal de Goiás;Faculdade de Nutrição da Universidade Federal de Goiás
Outcome results
None listed