Patients with HIV/AIDS and non-adherence to antiretroviral therapy
Conditions
Interventions
The intervention group with Trial-Based Cognitive Therapy: 48 HIV-infected people will be divided in 8 groups of 6 people, they will have 14 sessions of psicological therapy , one session weekly , e
Behavioural
Sponsors
Fundação Bahiana de Infectologia
Universidade Federal de Bahia
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: HIV-infected patients with viral load higher than 500 copies/mL in the last two tests or virologic controlled due to non-adherence to antiretroviral therapy. Age between 18 and 65 years, to be able to write and follow the protocol's instructions and sign informed consent.
Exclusion criteria
Exclusion criteria: Difficult with reading and whitting activities; the patient can not participate in another psychological therapy, and he can not have psychiatric or clinical diagnosis that interferes in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the higher antiretroviral therapy adherence that will be measured by the instruments: 1. Adherence Self-Report ACTG Questionnaire that considers adherents the subjects with drug using frequency igual or more than 95%; 2. the laboratory test result of HIV-RNA viral load is equal to <50 copies. The analysis will be performed in baseline, three and six months after the intervention in each group, and comparing the intervention group with the control group.;- | — |
Secondary
| Measure | Time frame |
|---|---|
| Decrease of depression measured by questionnaire: Beck Depression Inventory- version II (BDI-II) which classifies in four levels according to validated scores for Brazilian population: minimal (0-11), moderate (12-19), mild (20-35), and severe (36-63). The analysis will be performed in baseline, three and six months after the intervention in each group, and comparing the intervention group with the control group.;Decrease of Anxiety measured by questionnaire: Beck Anxiety Inventory (BAI) which classifies in four levels according to validated scores for Brazilian population: minimal (0-10), moderate (11-19), mild (20-30), and severe (31-63). The analysis will be performed in baseline, three and six months after the intervention in each group, and comparing the intervention group with the control group.;the improvement of quality of life, measured by the SF36 questionnaire Brazilian version considering the component results related to the mental health, physical health and general health. The analysis will be performed in baseline, three and six months after the intervention in each group, and comparing the intervention group with the control group. | — |
Countries
Brazil
Contacts
Public ContactMónica Narváez Betancur
Universidade Federal de Bahia
Outcome results
None listed