Postoperative Cognitive Dysfunction
Conditions
Interventions
Patients between 50 and 70 years old who undergo robot-assisted laparoscopic radical prostatectomy at Hospital Brasília Lago Sul will be invited to participate in the observational study and, after si
Sponsors
Hospital Brasília
Hospital Brasília
Eligibility
Sex/Gender
Male
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: Adult patients (between 50 and 70 years old) admitted to the participating center; undergoing robot-assisted laparoscopic radical prostatectomy surgery; american Society of Anesthesiology (ASA) physical status 1 to 3; body mass index between 18 and 35; education greater than or equal to 5 years; having signed an informed consent; no history of brain disease, dementia or other psychiatric disorders that affect cognition;
Exclusion criteria
Exclusion criteria: Surgeries lasting less than and equal to 1 hour; patient referred to the Intensive Care Unit; severe hearing or visual impairment;legally protected adults (under judicial protection, guardianship or supervision), persons deprived of their liberty;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We expect to find the incidence of postoperative cognitive dysfunction in men aged 50 to 70 years undergoing robot-assisted laparoscopic radical prostatectomy surgery. This will be obtained with the Montreal Cognitive Assessment test, which will indicate the presence of cognitive dysfunction if the participant scores less than 26 points in the second cognitive assessment. We will observe the incidence of cognitive dysfunction in the evaluated population and it is expected to obtain a value between 10 and 20% based on studies related to other major surgeries. | — |
Secondary
| Measure | Time frame |
|---|---|
| We expect to find an association between age and postoperative cognitive dysfunction in men aged 50 to 70 years undergoing robot-assisted laparoscopic radical prostatectomy surgery. This will be obtained by assessing the normality of the data using the Shapiro-Wilk test and the Student's t test or Mann-Whitney test will be used based on the result. We will associate cognitive dysfunction with age in the evaluated population and expect to obtain a higher percentage of dysfunction in older participants based on studies related to other major surgeries.;It is expected to find an association between duration of anesthesia and postoperative cognitive dysfunction in men aged 50 to 70 years undergoing robot-assisted laparoscopic radical prostatectomy surgery. This will be obtained by evaluating the normality of the data using the Shapiro-Wilk test and based on the result, Student's T or Mann-Whitney tests will be used. We will associate cognitive dysfunction with anesthesia duration in the evaluated population and it is expected to obtain a higher percentage of dysfunction in participants with longer anesthesia duration based on studies related to other major surgeries.;It is expected to find an association between days of hospitalization and postoperative cognitive dysfunction in men aged 50 to 70 years who underwent robot-assisted laparoscopic radical prostatectomy surgery. This will be obtained by evaluating the normality of the data using the Shapiro-Wilk test and based on the result, Student's T or Mann-Whitney tests will be used. We will associate cognitive dysfunction with length of hospital stay in the evaluated population and it is expected to obtain a higher percentage of dysfunction in participants with longer length of stay based on studies related to other major surgeries.;It is expected to find an association between the use of benzodiazepines and postoperative cognitive dysfunction in men aged 50 to 70 years who underwent robot-assisted laparoscopic radical | — |
Countries
Brazil
Contacts
Public ContactEwerton sobreira
Hospital Brasília
Outcome results
None listed