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Oral use of Oats in humans

The use of oat Beta-Glucan as a bioactive agent in the treatment of Dyslipidemias

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8qf7srs
Enrollment
45
Registered
2026-03-03
Start date
2021-01-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholesterol Cardiovascular Diseases

Interventions

This is an experimental study with a quantitative, randomized, blinded, placebo-controlled approach, involving collaborators and students from the Regional University of the Northwest of the State of
s health monitoring sector, confirming the sample size. To this end, participants will be divided into three groups of 15 people for each dose, and within each group, three subgroups will be formed to

Sponsors

Universidade Regional do Noroeste do Estado do Rio Grande do Sul
Lead Sponsor
Universidade Regional do Noroeste do Estado do Rio Grande do Sul
Collaborator

Eligibility

Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Collaborating individuals from the Regional University of the Northwest of the State of Rio Grande do Sul (UNIJUÍ); who are between 18 and 50 years old; both sexes; those with dyslipidemia

Exclusion criteria

Exclusion criteria: Pregnant women; use cholesterol medications; who do not accept to participate in the research; who do not sign the Free and Informed Consent form

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: Positive effects on the reduction and control of dyslipidemia were expected, through the use of the product developed for oral ingestion, with the analysis of biomarkers.;Outcome found 1: Reduction in total cholesterol

Secondary

MeasureTime frame
Expected outcome 2: Through the analysis of biomarkers of oxidative stress, such as: Catalase, Superoxide Dismutase, NP-SH (Non-Protein Sulfhydryls), Tissue Lipoperoxidation, Glutathione Reductase, Glutathione Peroxidase and Carbonylated Proteins, benefits were expected in using the product.;Outcome found 2: Antioxidant effects of beta-glucan were observed, with alterations in tissue lipid peroxidation and NP-SH (non-protein sulfhydryl groups)

Countries

BR

Contacts

Public ContactChristiane Colet

Universidade Regional do Noroeste do Estado do Rio Grande do Sul

christiane.colet@unijui.edu.br55-55-33320200

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Apr 4, 2026