Dentin sensitivity, Tooth bleaching
Conditions
Interventions
It will be a study the split-mouth type.
Experimental group: For one hundred twenty volunteers will be applied on the buccal surface of the teeth of a hemi arch (upper and lower) the desensitizing for
Drug
Other
Sponsors
Universidade Estadual de Ponta Grossa - UEPG
Universidade Estadual de Ponta Grossa - UEPG
Eligibility
Inclusion criteria
Inclusion criteria: Patients older than 18 years are included; with good oral and general health; with the maxillary anterior teeth free restorations and presenting no carious lesion; which possess the color of teeth A2 or darker depending on the color scale Vita Classical (Vita Zahnfabrik, Bad Säckingen, Germany) and to agree with the free and informed consent form.
Exclusion criteria
Exclusion criteria: Patients will be excluded who have already performed dental whitening, pregnant patients or lactating; who report tooth sensitivity; severe browning (staining by tetracycline, fluorosis or endodontics); with deleterious habits; people with dental prostheses and orthodontic appliances and any other oral pathology. Although patients will be excluded that present systemic changes such as stomach, heart, kidney and liver problems; diabetes; hypertension or are making continual use of drugs with analgesic and anti-inflammatory or who have allergies to Dipyrone.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Number of patients that report spontaneous pain in any moment of the bleaching protocol and up to 48 h post-bleaching, through self-report. This number will be presented as percentage of patients with tooth sensitivity and will be named absolute risk of tooth sensitivity.;Result obtained 1: The topical application of dipyrone was not able to reduce the absolute risk of dental sensitivity. No statistically significant difference was found between the groups in relation to absolute risk (Dipyrone group 83% and placebo group 90%, p = 0.09). Patients self-reported spontaneous pain at some time during the dental bleaching technique and up to 48 hours after the procedure. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: The intensity of tooth sensitivity will be assessed using the numeric 5-point scale (NRS 0-4), the values presented as median (1st and 3rd interquartile intervals) and the visual analogue scale (VAS 0-10) and will be presented as means and standard deviations; in different periods (during dental bleaching, up to 1 h, 1 h to 24 h and 24 h to 48 h post-bleaching).;Result obtained 2: Topical application of dipyrone was not able to reduce the intensity of dental sensitivity. The tooth sensitivity data under the two pain scales (NRS e VAS), were statistically similar, except from the period up to 1 h, where a significant difference (p = 0.02), was detected favoring the dipyrone group. When using the NRS scale, the following results were found: immediately (dipyrone group: 0 (0/0) and placebo group 1 (0/2), p = 0.76); up to 1 h (Dipyrone group: 1 (0/2) and placebo group 1 (0.5 / 2), p = 0.02); up to 24 h (dipyrone group: 1 (0/2) and placebo group 1 (0/2), p = 0.88) and up to 48 h (Dipyrone group: 0 (0/0) and placebo group 0 (0 / 0), p = 0.79). When using the VAS scale, the following results were found: immediately (dipyrone group: 1.7 ± 2.5 and placebo group 1.8 ± 2.4, p = 0.92); up to 1 h (Dipyrone group: 2.3 ± 2.7 and placebo group 2.6 ± 2.8, p = 0.09); up to 24 h (dipyrone group: 1.6 ± 2.3 and placebo group 1.8 ± 2.5, p = 0.17) and up to 48 h (Dipyrone group: 0.4 ± 1.0 and placebo group 0.3 ± 1.0, p = 0.07).;Expected outcome 3: The difference in color between the baseline condition and 1 month post-bleaching will be assessed by Vita Classical and Bleachedguide Vita shade guide as well as with the Vita Easyshade spectrophotometer. The data will be presented as means and standard deviations.;Expected outcome 3: Topical application of dipyrone does not interfere with the effectiveness of tooth whitening. The results of the analyses using scales Vita Classical (Dipyrone group 4.3 ± 2.5 and placebo group 4.5 ± 2.4, p = 0.30); Vita Bleachedguide (Dipyron | — |
Countries
Brazil
Contacts
Public ContactAlessandra Reis
Universidade Estadual de Ponta Grossa - UEPG
Outcome results
None listed