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Effect of a treatment for upper limb and language in post-stroke patients

Relationship between motor skill and language post-stroke and use of neuromodulation associated with peripheral therapies to improve movement, manual function and language

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8q65vps
Enrollment
Unknown
Registered
2022-05-31
Start date
2021-12-20
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aphasia

Interventions

Thirty male and female adults will participate in this study and will be randomly allocated to the neuromodulation and motor therapy group, neuromodulation and language therapy group or control group
E02.331.750

Sponsors

Universidade Federal de Sergipe
Lead Sponsor
Programa de Pós-graduação em ciências aplicadas à Saúde (PPGCAS)
Collaborator

Eligibility

Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients aged between 30 and 80 years will be included; of both sexes, diagnosis of ischemic or hemorrhagic stroke confirmed by computed tomography or magnetic resonance imaging, absence of cognitive deficits (assessed by the MMSE - Mini Mental State Examination, score greater than 18 ; All degrees of motor impairment according to the classification Fugl-Meyer score (total score 0 to 66 points): severe (Fugl-Meyer score 0 to 15 points), severe or moderate (16 to 34 Fugl-Meyer points), moderate/mild (35-53 Fugl points -Meyer) and mild (54 to 66 Fugl Meyer points); Aphasic patients will be evaluated by the Boston Naming Test and Montreal-Toulouse Battery Test (MTL-Brazil), in all degrees of impairment: alert for neuropsychological deficit (- 1.0 and -1.5), moderate to severe deficit (-1.6 and -2.0), presence of very severe deficit (less than or equal to -2.0), does not suggest cognitive deficit (greater than - 1.0)

Exclusion criteria

Exclusion criteria: Patients who present the following conditions will be excluded: clinical evidence of multiple brain lesions or other associated neurological diseases; peripheral neuropathies, leprosy, fibromyalgia, rheumatoid arthritis; other upper and lower motor neuron pathologies; history of psychiatric illness including drug and alcohol abuse; orthopedic deformities installed in the upper limbs. Those who are undergoing rehabilitation treatment during the collection (Occupational Physiotherapy and/or Speech Therapy) will not participate in the research. Patients with receptive types of aphasia (assessed by the MTL-Brazil test) will also be excluded. In addition to these, due to contraindication for the application of tDCS, patients with intracranial metallic implants will be excluded; pregnancy; use of medication that interferes with cortical excitability; history of seizures and/or epilepsy.

Design outcomes

Primary

MeasureTime frame
It is expected to find a relationship between upper limb motor function and language functions by the degree of impairment of these skills in order to establish a predictive factor of recovery and to investigate whether central therapy associated with peripheral may be superior to increase function in both. the functions (motor and language)

Secondary

MeasureTime frame
We will observe the motor and language skills by level of severity of the injury, as well as the correlation of upper limb motor function with language

Countries

Brazil

Contacts

Public ContactValquiria Seixas

Universidade Federal de Sergipe

valquiriamseixas@academico.ufs.br+55-079-36322082

Outcome results

None listed

Source: REBEC (via WHO ICTRP)