Use of laser therapy to reduce pain and improve recovery after wisdom tooth removal

Randomized double-blind split-mouth clinical trial evaluating the use of low-level laser therapy in the postoperative period following third molar surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

REBEC

Registry ID

RBR-8q234nn

Enrollment

Registered

2026-07-24

Start date

2026-08-13

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low-Level Light Therapy Dentistry

Interventions

This is a randomized, double-blind, split-mouth clinical trial. A total of 40 participants will be enrolled, corresponding to 40 experimental sites, with each participant undergoing two third molar su

Eligibility

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Male and female participants; aged between 18 and 30 years; clinically healthy and without comorbidities; presenting bilaterally impacted maxillary third molars in a distoangular position

Exclusion criteria

Exclusion criteria: Participants with systemic diseases, even if controlled; allergy to any component of the local haemostatic agent used in the study; neurological or psychiatric disorders; routine use of anti-inflammatory medications; history of photosensitivity; acute pericoronitis; advanced periodontal disease; pregnant or breastfeeding women

Design outcomes

Primary

Measure	Time frame
To evaluate postoperative pain intensity following the extraction of impacted maxillary third molars at surgical sites treated with low-level light therapy (880 nm) compared with control sites. Pain will be assessed using the Visual Analogue Scale (VAS) at 6, 12, 24, 48 and 72 hours and 7 days after surgery. Mean pain scores at each evaluation time point and differences between treatments will be analysed to determine the effect of the intervention.	—

Measure

Time frame

To evaluate postoperative pain intensity following the extraction of impacted maxillary third molars at surgical sites treated with low-level light therapy (880 nm) compared with control sites. Pain will be assessed using the Visual Analogue Scale (VAS) at 6, 12, 24, 48 and 72 hours and 7 days after surgery. Mean pain scores at each evaluation time point and differences between treatments will be analysed to determine the effect of the intervention.

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Secondary

Measure	Time frame
To evaluate postoperative facial swelling, trismus and wound healing following impacted maxillary third molar extraction at surgical sites treated with low-level light therapy compared with control sites. Facial swelling will be assessed using standardised facial measurements, trismus will be measured by maximum mouth opening using a caliper or millimetre ruler, and wound healing will be clinically evaluated using standardised criteria. Differences between treatments will be analysed at the predefined postoperative time points.	—

Measure

Time frame

To evaluate postoperative facial swelling, trismus and wound healing following impacted maxillary third molar extraction at surgical sites treated with low-level light therapy compared with control sites. Facial swelling will be assessed using standardised facial measurements, trismus will be measured by maximum mouth opening using a caliper or millimetre ruler, and wound healing will be clinically evaluated using standardised criteria. Differences between treatments will be analysed at the predefined postoperative time points.

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Countries

Contacts

Public ContactRodrigo Resende

Universidade Iguaçu

rresende@id.uff.br+55(21)997399282

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Aug 10, 2026