Jaw Abnormalities
Conditions
Interventions
No control group, only experimental: 16 patients.
Topical anesthetic based on benzocaine 200 mg / g, for 1 minute, prior to the injection. Bilateral application of 4U of botulin toxin in the elevator
Procedure/surgery
Sponsors
Faculdade de Odontologia da Universidade Federal do Rio Grande do Sul
Faculdade de Odontologia da Universidade Federal do Rio Grande do Sul
Eligibility
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Patients aged between 18 and 40 years, who presented gingival exposure when smiling, greater than or equal to 3 mm, bilaterally.
Exclusion criteria
Exclusion criteria: patients with systemic impairment, a history of hypersensitivity to the toxin, immunodeficiencies or who had applied the toxin less than six months ago; patients who received treatment with aminoglycosides, anticholinergic drugs or other agents that could interfere with neuromuscular transmissions or muscle relaxants (as the effect of botulinum toxin can be enhanced); patients with neuropathic diseases of the peripheral system, sclerosis or any disorders of the neuromuscular junction due to the increased risk of clinically significant adverse reactions; patients with infection at the application site, psychologically unstable or pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gingival exposure assessed longitudinally after application of botulinum toxin. | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events resulting from the application of botulinum toxin to assess risks and discomfort; | — |
Countries
Brazil
Contacts
Public ContactFernando Andriola
Faculdade de Odontologia da Universidade Federal do Rio Grande do Sul
Outcome results
None listed