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Lidocaine in reducing unwanted effects during awakening from general anesthesia and associated respiratory complaints

Lidocaine on reduction of emergence phenomena during general anesthesia and respiratory complaints after Tracheal Intubation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8p4sy6
Enrollment
Unknown
Registered
2020-07-09
Start date
2020-01-27
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough

Interventions

General anesthesia with orotracheal intubation, cannula 7.0 for women and 8.0 for men. Group 1: 14 participants, filling the tracheal cannula cuff with air (placebo). Group 2: 14 participants, topical
Procedure/surgery
V03.175.250

Sponsors

Victor Cáppia
Lead Sponsor
Universidade de Marília
Collaborator

Eligibility

Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients physical status ASA (American Society of Anesthesiologists) I and II. Elective surgeries with an expected duration of 60 to 180 minutes. General anesthesia with orotracheal intubation.

Exclusion criteria

Exclusion criteria: Smoking. Orotracheal intubation performed in more than 2 attempts. Body mass index greater than 35 kg/m2. Chronic use of corticosteroids. Recent history of upper airway infection (less than 21 days). Otorhinolaryngological or head / neck surgeries. Risk of bronchoaspiration. History of allergy to any of the drugs used in the protocol.

Design outcomes

Primary

MeasureTime frame
Sore throat 1 hour and 24 hours after removal of the tracheal cannula, using the visual analogue pain scale (numbered from 0 = no pain to 10 = maximum pain).

Secondary

MeasureTime frame
Measurement of cough during tracheal cannula removal, 1 hour and 24 hours later, using the Minogue cough scale (grade 1: isolated cough / grade 2: more than one episode of non-sustained cough lasting less than 5 seconds / grade 3: sustained cough lasting more than 5 seconds).;Hemodynamic changes (systolic, diastolic and mean blood pressure, and heart rate) 3 minutes before tracheal extubation and immediately after.;Hoarseness incidence 1 hour and 24 hours after tracheal extubation, by division into 3 degrees (grade 1: noted by the participant, grade 2: obvious to the observer, grade 3: aphonia).;Dysphagia incidence 1 hour and 24 hours after tracheal extubation.;Incidence of foreign body sensation 1 hour and 24 hours after removal of the tracheal cannula.

Countries

Brazil

Contacts

Public ContactVictor Cáppia

Victor Cáppia

victor_cappia@hotmail.com+55 14 991340021

Outcome results

None listed

Source: REBEC (via WHO ICTRP)