Ascorbic Acid Pressure Ulcer
Conditions
Interventions
This is a randomized, controlled, two-arm, parallel, single-blind (evaluator-blinded) clinical trial that will assess the effectiveness of topical ascorbic acid in the healing of pressure injuries. El
s routine. Blinding will be simple, with t
Sponsors
Universidade Federal Rural da Amazonia
Instituto de Ciências da Saúde da Universidade Federal do Pará
Eligibility
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Individuals of both sexes; between 18 and 90 years; no history of allergy to Ascorbic Acid; under home care; with Stage II or III Pressure Injury; and a score of 15 on the Pressure Ulcer Scale for Healing (PUSH)
Exclusion criteria
Exclusion criteria: Volunteers with pressure injuries in stages other than II or III; presence of uncontrolled systemic or local infection in the injury; concomitant use of topical or systemic therapies that may interfere with the healing process; severe or decompensated clinical conditions that prevent home follow-up; communication difficulties that make data collection impossible; absence of a caregiver when necessary for managing the injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| o evaluate the effectiveness of 10% topical ascorbic acid in the healing of pressure sores. A reduction in the time to complete wound healing is expected in the intervention group compared to the control group. This will be verified through systematic clinical follow-up and serial assessment of the lesions. The total time, in days, until complete wound healing will be observed, considering total epithelialization without exudate, as well as the proportion of healed lesions at the end of up to 8 weeks of follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate the evolution of tissue in the wound bed. A faster improvement in tissue pattern (granulation and epithelialization) is expected in the intervention group. This will be verified through standardized clinical assessment. The percentage of granulation and epithelialization tissue will be observed over time. ;Evaluate the depth of pressure injuries. A more significant reduction in depth is expected in the intervention group. This will be verified through measurement with an appropriate sterile instrument. The value in centimeters of the lesion depth will be observed throughout the follow-up period. | — |
Countries
BR
Contacts
Public ContactVinicius Lino Souza Neto
Universidade Federal Rural da Amazonia
Outcome results
None listed