Pulmonary Disease, Chronic Obstructive
Conditions
Interventions
It is proposed to carry out a controlled and randomized clinical trial. The study will include five groups that are undergoing clinical monitoring, namely: Group 1 (Resistance Training), Group 2 (Resi
E02.760.169.063.500.387.875
E02.331.750
Sponsors
Instituto de Educação Superior da Paraíba - IESP
Universidade Federal da Paraiba
Eligibility
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: Subjects diagnosed with mild or moderate Chronic Obstructive Pulmonary Disease - COPD according to the Global Initiative for Chronic Obstructive Lung Disease criteria (GOLD 1: Forced expiratory volume in the first second (FEV1) mild = 80% of predicted, GOLD 2: 50% moderate = FEV1 <80% of predicted); of both sexes; aged between 45 and 75 years; and classified as sedentary or insufficiently active (International Physical Activity Questionnaire - IPAQ, reduced version)
Exclusion criteria
Exclusion criteria: Individuals with acute exacerbation of Chronic Obstructive Pulmonary Disease - COPD, with unstable hemodynamic parameters (blood pressure <100mmHg systolic and <60mmHg for diastolic and Mean Arterial Pressure (MAP) <80mmHg), who have undergone surgery in the last 6 months; with a recent history of chest wall trauma or abdominal trauma; and/or substantial chest wall deformity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find an improvement in lung function that will be assessed through the spirometry test to be carried out before the start of the intervention and after the end of the 10-week intervention.;It is expected to find an improvement in respiratory muscle strength, which will be evaluated by measuring inspiratory and expiratory respiratory muscle pressures using an analogue manometer calibrated in cmH2O. Measurements will be taken before the start of the intervention and after the end of the 10-week intervention.;It is expected to find an improvement in respiratory, neuromuscular and mechanical efficiencies that will be evaluated through cardiopulmonary exercise testing (CPET) associated with electromyography (EMG) to be carried out before the start of the intervention and after the end of the 10-week intervention.;It is expected to find a reduction in fatigue that will be assessed with the application of the visual analogue scale (VAFS) to be applied before the start of the intervention and after the end of the 10-week intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find an improvement in functional capacity that will be evaluated with the application of the six-minute walk test (6MWT) to be applied before the start of the intervention and after the end of the 10-week intervention.;It is expected to find an improvement in peripheral muscle strength that will be evaluated with the application of the 1 Repetition Maximum (1RM) test to be carried out before the start of the intervention and after the end of the 10-week intervention.;It is expected to find a reduction in dyspnea that will be evaluated with the application of the COPD Assessment Test (CAT) to be applied before the start of the intervention and after the end of the 10-week intervention.;It is expected to find an improvement in diaphragmatic function that will be evaluated through measurements of mobility, thickness and thickening fraction of the diaphragm through diaphragmatic ultrasound to be performed before the start of the intervention and after the end of the 10-week intervention.;It is expected to find an improvement in peripheral muscle quality that will be evaluated through measurements of quadriceps muscle thickness (EMQ) and cross-sectional area of the rectus femoris through kinesiological ultrasound of the quadriceps to be performed before the start of the intervention and after the end of the 10-week intervention.;It is expected to find an improvement in body composition that will be evaluated with densitometry and bioimpedance tests to be carried out before the start of the intervention and after the end of the 10-week intervention.;It is expected to find an improvement in quality of life that will be assessed through the application of the St. George’s Respiratory Questionnaire to be applied before the start of the intervention and after the end of the 10-week intervention. | — |
Countries
Brazil
Contacts
Public ContactMaria do Socorro Brasileiro-Santos
Universidade Federal da Paraiba
Outcome results
None listed