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Efficacy mouthwash developed with vegetable oils

Clinical study of the efficacy of oral rinse-containing vegetable oils for the control of dental biofilm

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
REBEC
Registry ID
RBR-8nr8xy
Enrollment
Unknown
Registered
2017-12-18
Start date
2016-10-04
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental plaque Prevention and control

Interventions

Sixty young adults will be selected as the sample for the study, which will be randomly divided into 4 groups. Like this: Group 1: should be composed of 15 volunteers who will use common fluoride toot
Other

Sponsors

Universidade Federal do Pará
Lead Sponsor
Universidade Federal do Pará
Collaborator

Eligibility

Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Be between 18 and 30 years old; both sexes; presence of at least 70% of teeth in the arches; absence of oral pathologies not related to the dental biofilm; present at least 40% of biofilm in the dental faces evidenced in the initial examination.

Exclusion criteria

Exclusion criteria: Smoking; pregnants; recent or current use of antibiotics and medicines that alter salivary flow; being on radiotherapy or chemotherapy; present systemic diseases that generate oral manifestations; presence of periodontal disease or active carious lesions; presence of dental calculus; make use of orthodontic appliance or occlusal plates; do not accept to signing the free and informed consent form.

Design outcomes

Primary

MeasureTime frame
It is expected to reduce the mean of the dental biofilm deposited on the dental surfaces after 21 days, when compared to the initial plaque index (measured at time 0), by intervention groups that will use chemical agents such as mouthwashes.;The experimental oral rinse with vegetable oils, tested in Group 2 of intervention, is expected to reduce plaque in a quantity equal to or greater than the other chemical agents used in intervention groups 1 and 3.;The mouth rinses tested in intervention groups 1, 2 and 3 are expected to be able to further reduce the amount of bacterial plaque when compared to intervention group 4, which will not use chemical agents for plaque control.

Secondary

MeasureTime frame
It is expected that the evaluated products do not cause adverse effects on the sample during the study period, as well as that the experimental oral rinse with vegetable oils is well accepted and well tolerated by the research volunteers.

Countries

Brazil

Contacts

Public ContactDanielle Emmi

Universidade Federal do Pará

dtemmi@yahoo.com.br+55(91)3201-7494

Outcome results

None listed

Source: REBEC (via WHO ICTRP)