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The effect of Cajuína consumption in untrained individuals

The effects of Cajuína supplementation in individuals untrained subjects submitted to an Acute session of high intensity exercise: a randomized, double-blind follow-up of 72 hours

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
REBEC
Registry ID
RBR-8n5ndqj
Enrollment
Unknown
Registered
2026-01-07
Start date
2024-07-06
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A total of 13 untrained participants were recruited for the study in the period between July and September 2024. To be recruited, volunteers should meet some criteria: at least 6 months without regular physical exercise

Interventions

This is a randomized controlled trial of two arms with double masking in which thirteen physically untrained male participants were randomly allocated through a computer-generated randomization sequen

Sponsors

Universidade federal do ceará
Lead Sponsor
Universidade estadual vale do acaraú
Collaborator

Eligibility

Sex/Gender
Male
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Male individuals; age between 18 and 40 years; physically untrained; body mass between 60 and 100 kilograms; body mass index between 18.5 and 29.9 kilograms per square meter; absence of regular structured physical exercise in the last six months; Clinically healthy; no regular use of antioxidant supplements; no continuous use of medications; fit for intense physical exercise

Exclusion criteria

Exclusion criteria: Current smoking; regular consumption of alcoholic beverages; use of illicit drugs; prior diagnosis of cardiovascular metabolic neurologic musculoskeletal liver renal, hematological or respiratory diseases; history of food intolerance to the components of the intervention; use of drugs or supplements with potential antioxidant effect in the last three months; presence of musculoskeletal injuries that prevent intense physical exercise

Design outcomes

Primary

MeasureTime frame
Expected outcome 1 Wait-if cajuina supplementation reduces oxidative stress induced by intense physical exercise evaluated through the decrease of lipid peroxidation markers and reactive oxygen species measured in blood samples collected at rest and immediately after physical exercise;Outcome found 1 A reduction of oxidative stress induced by intense physical exercise was observed in the cajuína group compared to the placebo group evidenced by the decrease in markers of lipid peroxidation and reactive oxygen species measured in blood samples collected in rest and immediately after physical exercise

Secondary

MeasureTime frame
Expected outcome 2 Cajuina supplementation is expected to mitigate tissue damage induced by intense physical exercise evaluated through reduction of serum levels of creatine kinase and lactate dehydrogenase measured before and after exercise;Outcome found 2 Attenuation of tissue damage induced by intense physical exercise was observed in the cajuína group compared to the placebo group evidenced by the reduction of serum levels of creatine kinase and lactate dehydrogenase after physical exercise;Expected outcome 3 Cajuina supplementation is expected to cause changes in hematological parameters in response to intense physical exercise evaluated by counting red blood cells mean corpuscular volume and hemoglobin concentration measured at rest and after physical exercise;Outcome found 3 Discrete changes in hematological parameters were observed in the cajuína group compared to the placebo group, characterized by a slight increase in red blood cell count and mean corpuscular volume after intense physical exercise

Countries

Brazil

Contacts

Public ContactJose klinger Oliveira

Universidade Federal do Ceará

klingeroliveira123@gmail.com+55 (88) 99447-5264

Outcome results

None listed

Source: REBEC (via WHO ICTRP)