Obesity
Conditions
Interventions
Experimental sessions will consist of oral administration of the angiotensin II type 1 receptor blocker (40 mg) or oral administration of placebo. The hemodynamic evaluations will be composed by deter
Drug
Other
Sponsors
Universidade Federal Fluminense
Universidade Federal Fluminense
Eligibility
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Age between 20 and 50 years; both sexes; body mass index between 25 kg.m-2 and 35 kg.min-2; absence of any chronic diseases (hypertension, diabetes, chronic kidney disease, heart failure, among others, except obesity) and musculoskeletal abnormalities; do not practice physical activity regularly (exercise lasting less than 30 minutes three times a week); and do not make regular use of medications such as vitamins or anti-inflammatory drugs.
Exclusion criteria
Exclusion criteria: Menopausal or postmenopausal women; smokers; athletes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in endothelial function assessed by increased flow-mediated dilation before, thirty minutes and sixty minutes after acute mental stress in overweight / obese grade I men and women from a p value less than or equal to 0, 05 in pre and post intervention comparisons | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in the behavior of vascular and oxidative variables in response to mental stress in grade I overweight / obese men and women, from the finding of a p value less than or equal to 0.05 in pre and post intervention comparisons | — |
Countries
Brazil
Contacts
Public ContactNatalia Rocha
Universidade Federal Fluminense
Outcome results
None listed