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Effects of interval running and cranberry supplementation on the immune system

Effects of interval training and cranberry supplementation in immunomodulation: randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8mpyq4
Enrollment
Unknown
Registered
2018-09-12
Start date
2018-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High-Intensity Interval Training

Interventions

Group supplemented with cranberry (n = 15 subjects) - CRA: 1 daily dose of cranberry extract (PAC Standardized cranberry extract), in capsule, offering 36mg of PACs, maintained for two weeks and perfo
Dietary supplement
SP6.051.227

Sponsors

Universidade Federal de Sergipe
Lead Sponsor
Universidade Federal de Sergipe
Collaborator

Eligibility

Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Present VO2max classification between 35 and 55 ml.kg-1.min-1; be engaged in running training for at least three times a week; has no musculoskeletal disorder, autoimmune, cardiac, pulmonary or hypersensitivity disease; not use anti-inflammatory drugs or food supplements, including substances with antioxidant function, at least 30 days before the study period.

Exclusion criteria

Exclusion criteria: Do not meet 100% of the number of sprints in one or more high intensity interval training (HIIT) protocols; do not carry out any of the pre or post evaluation of HIIT; if they are absent in one of the six sessions of HIIT; present any injury or motor impairment to perform HIIT; present any infection of the upper respiratory tract during the experiment; antibiotic use within six months prior to study; regularly consume any dietary supplement composed of vitamins, minerals or bioactive compounds; do not consume any of the doses of cranberry proposed for the supplementation stage; present known allergy or intolerance to cranberry products.

Design outcomes

Primary

MeasureTime frame
It is believed that cortisol concentration will not be influenced by supplementation of Cranberry. On the other hand, after two weeks of high intensity interval training, the cranberry group will be able to reverse the effects of the accumulated training load while placebo will only show attenuation.

Secondary

MeasureTime frame
It is expected that the HIIT protocols used in this study will be able to induce transient immunosuppression, associated with oxidative stress and muscle damage. It is also expected that there will be an attenuation in this immunosuppression after six training sessions.

Countries

Brazil

Contacts

Public ContactAna Mara Silva

Universidade Federal de Sergipe

anamaraufs@gmail.com+55-079-991917075

Outcome results

None listed

Source: REBEC (via WHO ICTRP)