Ureteral Calculi
Conditions
Interventions
This is a randomized, controlled, two-arm, single-blind clinical trial. The experimental group will include 55 adult patients with ureteral stones undergoing transureteroscopic ureterolithotripsy with
Sponsors
University of São Paulo
University of Pittsburgh
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Consecutive patients aged over 18 years with symptomatic ureterolithiasis; who underwent primary lithotripsy at the Endourology Unit or the Emergency Department of the Hospital das Clínicas, Faculty of Medicine, University of São Paulo
Exclusion criteria
Exclusion criteria: Patients undergoing retreatment; pregnant women; those unable to continue treatment at the Institution; patients with ureteral stones smaller than 5 mm or larger than 15 mm; patients with active urinary tract infection or with coagulopathies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected Outcome 1: Measurement of carbon dioxide emissions involved in the lithotripsy process (ureteroscopy and extracorporeal shock wave lithotripsy), calculated through Life Cycle Assessment (LCA) using the Ecoinvent database. The outcome will be expressed as carbon dioxide equivalent (CO2e) per cubic centimeter of treated stone.;Observed Outcome 1: An average carbon dioxide equivalent (CO2e) emission of 26.7 kg per patient was observed in the ULT group, and 9.4 kg per patient in the ESWL group. Data were obtained through Life Cycle Assessment (LCA), considering materials, energy, hospital usage, and waste disposal. It was confirmed that ULT has a greater environmental impact than ESWL. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected Outcome 1: To evaluate the efficiency of stone fragmentation by the amount of carbon dioxide emitted, as well as to analyze the materials involved in the processes. The assessment will be carried out through clinical and tomographic evaluation at 30 days postoperatively, combined with emission estimates based on Life Cycle Assessment (LCA) methodology and the Ecoinvent database.;Observed Outcome 1: A complete stone resolution rate of 93% was observed in the ULT group and 71% in the ESWL group. Data were obtained through imaging exams performed four weeks after the procedure, using the absence of fragments =4 mm as the success criterion. | — |
Countries
Brazil
Contacts
Public ContactCaio Suartz
Universidade de Sao paulo
Outcome results
None listed